|
Variable
|
AUC
|
95% CI
|
P
|
Optimal cut-off value
|
Sensitivity (%)
|
Specificity (%)
|
|---|
|
PRISM III score
|
0.92
|
0.84–0.99
|
< 0.001
|
7.5
|
90.9
|
77.4
|
|
sCysC, mg/L
|
0.89
|
0.82–0.97
|
< 0.001
|
0.81
|
90.9
|
78.2
|
|
uCysC, ng/mg uCr
|
0.88
|
0.76–0.99
|
< 0.001
|
1145.0
|
81.8
|
86.5
|
|
uIGFBP-7, ng/mg uCr
|
0.79
|
0.66–0.92
|
0.001
|
563.4
|
72.7
|
79.0
|
|
uIGFBP-7, combined with sCysC
|
0.89
|
0.79–0.99
|
< 0.001
| | | |
|
uIGFBP-7, combined with uCysC
|
0.88
|
0.79–0.98
|
< 0.001
| | | |
|
uIGFBP-7, combined with sCysC and uCysC
|
0.90
|
0.81–1.00
|
< 0.001
| | | |
- Severe AKI was defined as AKI network stages 2 and 3
- AKI acute kidney injury, AUC the area under the ROC curve, CI confidence interval, PRISM III pediatric risk of mortality III
