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Table 3 Association of variables with eGFR

From: Serum and urine FGF23 and IGFBP-7 for the prediction of acute kidney injury in critically ill children

Variable Univariate regression Multivariate regression
B coefficient (SE) P B coefficient (SE) P
Age, months 0.524 (0.025) < 0.001   
Body weight, kg 1.129 (0.067) < 0.001   
Gender −0.063 (0.062) 0.317   
PRISM III score 0.000 (0.006) 0.959   
MV −0.033 (0.063) 0.595   
Duration of MV, hours 0.000 (0.000) 0.302   
sFGF23, pg/mL −0.842 (0.108) < 0.001 −0.156 (0.075)a 0.040
sIGFBP-7, ng/mL −0.657(0.214) 0.003 −0.111 (0.113)a 0.327
sCysC, mg/L −1.062 (0.113) < 0.001 −0.702 (0.048)a < 0.001
uFGF23, pg/mg uCr −0.169 (0.051) 0.001 −0.050 (0.027)a 0.061
uIGFBP-7, ng/mg uCr −0.013 (0.065) 0.843   
uCysC, ng/mg uCr −0.097 (0.042) 0.022 −0.067 (0.020)a 0.001
  1. eGFR estimated glomerular filtration rate, MV mechanical ventilation, PRISM III pediatric risk of mortality III. eGFR was calculated based on age, body weight, and serum levels of creatinine and cystatin C
  2. aAfter adjustment for age and body weight. All continuous variables were log-transformed