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Table 3 Association of variables with eGFR

From: Serum and urine FGF23 and IGFBP-7 for the prediction of acute kidney injury in critically ill children

Variable

Univariate regression

Multivariate regression

B coefficient (SE)

P

B coefficient (SE)

P

Age, months

0.524 (0.025)

< 0.001

  

Body weight, kg

1.129 (0.067)

< 0.001

  

Gender

−0.063 (0.062)

0.317

  

PRISM III score

0.000 (0.006)

0.959

  

MV

−0.033 (0.063)

0.595

  

Duration of MV, hours

0.000 (0.000)

0.302

  

sFGF23, pg/mL

−0.842 (0.108)

< 0.001

−0.156 (0.075)a

0.040

sIGFBP-7, ng/mL

−0.657(0.214)

0.003

−0.111 (0.113)a

0.327

sCysC, mg/L

−1.062 (0.113)

< 0.001

−0.702 (0.048)a

< 0.001

uFGF23, pg/mg uCr

−0.169 (0.051)

0.001

−0.050 (0.027)a

0.061

uIGFBP-7, ng/mg uCr

−0.013 (0.065)

0.843

  

uCysC, ng/mg uCr

−0.097 (0.042)

0.022

−0.067 (0.020)a

0.001

  1. eGFR estimated glomerular filtration rate, MV mechanical ventilation, PRISM III pediatric risk of mortality III. eGFR was calculated based on age, body weight, and serum levels of creatinine and cystatin C
  2. aAfter adjustment for age and body weight. All continuous variables were log-transformed