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Table 2 Patient variables by drug (first course of drug therapy)

From: Ursodeoxycholic acid versus phenobarbital for cholestasis in the Neonatal Intensive Care Unit

 

Phenobarbital (N = 37)

Ursodiol (N = 31)

p-value

Gestational Age at Birth (%)

  

0.7628

 22–28 weeks

38

45

 28–34 weeks

40

32

  > 34 weeks

22

23

Male (%)

57

71

0.2261

Race (%)

  

0.1439

 Caucasian

58

61

 African American

20

32

 Other

22

7

IUGR (%)

19

32

0.2058

On Restricted Lipids at start of drug therapy (%)

46

39

0.5479

Length of Drug Course a

17 (13,38)

17 (12,32)

0.4557

Dose (mg/kg/day) a

4.48 (3.84, 5.05)

27.43 (22.39,29.00)

n/a

Direct Bilirubin at start of drug therapy

  

0.8458

mg/dLb

7.1 (3.98)

6.9 (4.92)

umol/L b

121.1 (68.1)

118.0 (84.2)

  1. a: Median (lower quartile, upper quartile); b: Mean (SD). IUGR = in utero growth restriction