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Table 3 Efficacy analysis

From: The antipyretic efficacy and safety of propacetamol compared with dexibuprofen in febrile children: a multicenter, randomized, double-blind, comparative, phase 3 clinical trial

Efficacy variable Study group (n = 125) Control group (n = 138) p-value
AUC of BT change at 6 h after administration-and-time relationship 5.98 ± 3.87 5.78 ± 4.01 0.683
BT reduction at 4 h after administration (°C) 0.97 ± 0.90 1.16 ± 0.92 0.09
Maximum value of BT reduction during the 6 h after administration (°C) 1.63 ± 0.66 1.64 ± 0.70 0.855
Number of patients whose BT normalized (< 37.0 °C) at 6 h after administration, n (%) 26 (20.8) 23 (16.7) 0.390
Time point when BT first reached < 37.0 °C, hour 1.73 ± 1.29 2.13 ± 1.06 0.064
  1. Results are presented as mean ± standard deviation or as a percentage (%)
  2. BT Body Temperature
  3. AUC Area Under the Curve