Table 1 Clinical and laboratory characteristics of children in different diagnostic groups (n = 295)
On admission | Definite LNB (n = 68) | Possible LNB (n = 35) | Non-LNB (n = 133) | Other diagnosis (n = 59) |
|---|---|---|---|---|
Gender | ||||
Female, n (%) | 30 (44) | 15 (43) | 83 (62) | 30 (51) |
Male, n (%) | 38 (56) | 20 (57) | 50 (38) | 29 (49) |
Age, median (range) | 6 (2–15) | 8 (4–15) | 13 (1–17) | 10 (0–17) |
Observed tick bite, n (%) | 41 (60) | 18 (51) | 59 (44) | 15 (25) |
Clinical characteristics | ||||
EM, n (%) | 28 (41) | 9 (26) | 18 (14) | 2 (3) |
Facial nerve palsy, n (%) | 46 (68) | 25 (71) | 51 (38) | 5 (8) |
Headache, n (%) | 49 (72) | 24 (69) | 94 (71) | 39 (66) |
Fatigue, n (%) | 62 (91) | 23 (66) | 88 (66) | 38 (64) |
Fever, n (%) | 37 (54) | 12 (34) | 23 (17) | 19 (32) |
Neck pain, n (%) | 36 (53) | 18 (51) | 35 (26) | 19 (32) |
Neck stiffness, n (%) | 23 (34) | 11 (31) | 19 (14) | 12 (20) |
Loss of appetite, n (%) | 43 (63) | 19 (54) | 46 (35) | 19 (32) |
Nausea, n (%) | 24 (35) | 12 (34) | 46 (35) | 23 (39) |
Vertigo, n (%) | 10 (15) | 7 (20) | 59 (44) | 24 (41) |
Laboratory findings | ||||
Pleocytosis, median (range) | 164 (20–890) | 85 (6–1125) | 0 (0–4) | 0 (0–634) |
Anti-Borrelia antibodies in CSF | ||||
IgG, n (%) | 18 (26) | 0 (0) | 0 (0) | 0 (0) |
IgM, n (%) | 18 (26) | 0 (0) | 0 (0) | 0 (0) |
IgG + IgM, n (%) | 32 (48) | 0 (0) | 0 (0) | 0 (0) |
Anti-Borrelia antibodies in serum | ||||
IgG, n (%) | NA | 0 (0) | 0 (0) | 0 (0) |
IgM, n (%) | NA | 1 (3) | 0 (0) | 0 (0) |
IgG + IgM, n (%) | NA | 19 (54) | 16 (12) | 1 (1) |
Antibiotic treatment, n (%) | 68 (100) | 35 (100) | 18 (11) | 8 (14) |