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Table 1 Guide for appraising NMA evidence

From: Network meta-analysis: users’ guide for pediatricians

Credibility

 Did the review explicitly address sensible question?

 Was the search for studies and selection comprehensive?

 Did the review assess evidence certainty?

 Did the review present results for the reader?

Certainty

 What is the risk of bias of included studies?

 Were the results precise?

 Were results consistent across studies?

 How trustworthy are the indirect comparisons?

 Were results consistent between direct and indirect comparisons?

 Is there evidence for publication bias?

 Were treatment ranks presented and were they trustworthy?

Applicability

 What is the overall quality of the evidence?

 What are the limitations of the evidence?

 Can I apply the results to my patients?