Skip to main content

Table 1 Congenital Rhabdomyosarcoma: review of the literature

From: Congenital Rhabdomyosarcoma: a different clinical presentation in two cases

Patient and disease characteristics ERMS ptse
(n = 16)
ARMS ptse
(n = 17)
Gender: female/male (sex ratio) 5/11 (0.45) 10/7 (1.4)
Primary site
 PM head & neck 1
 Non PM head & neck 6 4
 Orbit
 GU non bladder-prostate 2
 GU bladder-prostate 2
 Extremities 1 7
 Other site 5a 4b
 NA 1
IRSG
 I 1
 II 4 1
 III 11 3
 IV 1 13c
Molecular biology
 Negative 2 5
 NA 12 8
 PAX3-FOXO1 positive 3
 PAX7-FOXO1 positive
 Others 2 [t(2;8)] 1 [N-myc amplification]
Therapy
 NA 1
 Surgery only 2
 Chemotherapy only 2 9
 Chemotherapy + surgery 9 4
 Chemotherapy + surgery + radiotherapy 3 2
 Chemotherapy + radiotherapy 1
Outcome
 Alive [median months from dg (range)] 8 [31.5 (6–240)] 4 [9 (6–240)]
 Dead 2 13d
 NA 6
  1. ERMS embryonal rhabdomyosarcoma, ARMS alveolar rhabdomyosarcoma, pts. patients, PM parameningeal, n number, GU genito-urinary, NA not available, IRSG Intergroup Rhabdomyosarcoma Study Group, dg diagnosis
  2. a2-perineal, 2-chest wall, 1-trunk
  3. b2-trunk, 2-chest wall
  4. cFor all patients, cutaneous and subcutaneous tissue was a metastatic site
  5. d7/13 patients had central nervous system disease progression
  6. eData about family history of cancer were not available