Table 1 Congenital Rhabdomyosarcoma: review of the literature
From: Congenital Rhabdomyosarcoma: a different clinical presentation in two cases
| Patient and disease characteristics |
ERMS ptse (n = 16) |
ARMS ptse (n = 17) |
|---|---|---|
| Gender: female/male (sex ratio) | 5/11 (0.45) | 10/7 (1.4) |
| Primary site | ||
| PM head & neck | – | 1 |
| Non PM head & neck | 6 | 4 |
| Orbit | – | – |
| GU non bladder-prostate | 2 | – |
| GU bladder-prostate | 2 | – |
| Extremities | 1 | 7 |
| Other site | 5a | 4b |
| NA | – | 1 |
| IRSG | ||
| I | 1 | – |
| II | 4 | 1 |
| III | 11 | 3 |
| IV | 1 | 13c |
| Molecular biology | ||
| Negative | 2 | 5 |
| NA | 12 | 8 |
| PAX3-FOXO1 positive | – | 3 |
| PAX7-FOXO1 positive | – | – |
| Others | 2 [t(2;8)] | 1 [N-myc amplification] |
| Therapy | ||
| NA | – | 1 |
| Surgery only | 2 | – |
| Chemotherapy only | 2 | 9 |
| Chemotherapy + surgery | 9 | 4 |
| Chemotherapy + surgery + radiotherapy | 3 | 2 |
| Chemotherapy + radiotherapy | – | 1 |
| Outcome | ||
| Alive [median months from dg (range)] | 8 [31.5 (6–240)] | 4 [9 (6–240)] |
| Dead | 2 | 13d |
| NA | 6 | – |