Table 3 Variation in developmental and behavioral skills throughout the study
Evaluation | T0 | T1 | T2 | P-value Friedman |
|---|---|---|---|---|
VABS Communication (mean ± SD) | 15.8 ± 9.0 | 19.9 ± 10.0*** | 21.7 ± 11.2*** | 1.2 10−6 |
VABS Socialization (mean ± SD) | 12.8 ± 6.5 | 19.2 ± 7.6*** | 24.3 ± 13.4*** | 2.7 10− 6 |
Imitation Score Nadel (mean ± SD) | 9.6 ± 5.7 | 13.4 ± 7.1** | 14.3 ± 6.3** | 6.5 10−5 |
PEP-R Imitation (mean ± SD) | 11.2 ± 8.1 | 16.0 ± 11.8* | 18 ± 15.0** | 4.5 10− 5 |
PEP-R Verbal cognition (mean ± SD) | 17.6 ± 9.4 | 22 ± 13.0 | 20.9 ± 16.0 | 0,207 |
Global PEP-R (mean ± SD) | 25.7 ± 10.5 | 30.9 ± 13.5** | 33.5 ± 17.0*** | 5.83 10− 6 |
PEP-R Perception (mean ± SD) | 28.5 ± 12.6 | 38 ± 17.7** | 40.5 ± 17.1** | 4.48 10− 4 |
PEP-R Fine motor skills (mean ± SD) | 30.6 ± 14.7 | 35.2 ± 15.0* | 39.7 ± 17.2* | 0.0147 |
PEP-R Global motor skills (mean ± SD) | 32.3 ± 12.9 | 41.0 ± 14.4** | 34.0 ± 20.3 | 8.59 10− 3 |
PEP-R Oculo-manual development (mean ± SD) | 28.8 ± 14.5 | 35.5 ± 16.5* | 38.8 ± 18.2** | 1.12 10− 3 |
PEP-R Cognitive performance (mean ± SD) | 21.9 ± 14.8 | 25.5 ± 15.2 | 26.9 ± 19.0 | 0.0293 |
VABS Autonomy (mean ± SD) | 23.1 ± 9.7 | 27.2 ± 10.3*** | 32.1 ± 12.4*** | 9.87 10− 7 |
VABS Motricity (mean ± SD) | 31.6 ± 11.5 | 37.5 ± 12.4** | 38.5 ± 14.1** | 2.31 10− 4 |