Fig. 3

Comparison of evolution of CARS and VABS scores between 24 months of 3I methods (this study) and 36 months of standard treatment in centers according to Baghdadli et al., [48]. Evolution of the mean scores of CARS (panel a), VABS communication (Panel b), VABS socialization (Panel c) and VABS autonomy (Panel d) are represented in graphs. A linear regression was calculated for each treatment and the related equations are represented in the graphic. The ratio of the slopes (R s) indicate difference between the evolution of scores of Baghdadli et al., [48] and this study. A P-value calculated with the one sample t-test compare the distribution of the slope calculated for each subject with the mean slope of Baghdadli et al., [48]. * p-value < 0.05; **p-value < 0.01; *** p-value < 0.001