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Table 2 NICU stool samples positive for C. difficile by one or more modalities

From: Clostridium difficile stool shedding in infants hospitalized in two neonatal intensive care units is lower than previous point prevalence estimates using molecular diagnostic methods

Number of samples (n)

EIA GDH/toxin A/B

LAMP technology

Duplex PCR

(tpi/tcdB)

Cytotoxicity assay

2

−/−

Negative

Not done

+/−

Nontoxigenic C. difficile

Negative

4

+/+

Toxigenic

C. difficile

Positive

+/+

Toxigenic

C. difficile

Positive

2

+/+

Toxigenic

C. difficile

Positive

+/+

Toxigenic

C. difficile

Negative

7

+/−

Presumptive Nontoxigenic C. difficile

Negativea

−/−

Negative

Negative

  1. aone sample specimen was invalid