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Table 3 Angiogenic biomarkers tertiles and relative odds of death

From: Biomarkers of endothelial dysfunction predict sepsis mortality in young infants: a matched case-control study

Biomarker

N

Tertile 1

aOR

Tertile 2

aOR (95% CI)

Tertile 3

aOR (95% CI)

p-value for trend

Ang-1

70

1.00 (ref)

0.37 (0.09, 1.52)

0.39 (0.09, 1.62)

0.301

Ang-2

70

1.00 (ref)

1.39 (0.26, 7.36)

5.27 (1.15, 24.07)

0.061

Ang 2:1 ratio

70

1.00 (ref)

0.57 (0.09, 3.54)

4.82 (1.22, 19.03)

0.013

sICAM

70

1.00 (ref)

0.50 (0.09, 2.75)

2.43 (0.60, 9.90)

0.116

sVCAM

70

1.00 (ref)

0.95 (0.22, 4.11)

1.40 (0.36, 5.45)

0.834

  1. aOR adjusted odds ratio, CI confidence interval, Ang-1 angiopoietin-1, Ang-2 angiopoietin-2, Ang2:1 ratio of Ang-2 to Ang-1, sICAM soluble intercellular adhesion molecule-1, sVCAM soluble vascular adhesion molecule-1. P-value for trend using conditional logistic regression adjusted for sex, lethargy and prior antibiotic exposure
  2. Comparisons with p-value less than or equal to 0.05 marked in bold and 0.05–0.10 marked in italics