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Table 1 Patient characteristics

From: Elevated central venous pressure is associated with increased mortality in pediatric septic shock patients

Characteristics

Survivors (n = 159)

Non-survivors (n = 67)

p value

Age, years

4.0 (0.6, 12.7)

4.6 (0.8, 14.4)

0.273

Male, n (%)

83 (52.2)

33(49.3)

0.771

Coexisting conditions, n (%)

 Cardiac disease

44 (27.7)

12 (17.9)

0.132

 Hemato-oncologic disease

32 (20.1)

19 (28.4)

0.222

 Neurologic disease

25 (15.7)

7 (10.4)

0.404

 Pulmonary disease

20 (12.6)

13 (19.4)

0.216

 Chronic renal disease

20 (12.6)

7 (10.4)

0.667

 Gastrointestinal disease

12 (7.5)

6 (9.0)

0.789

 Endocrinologic disease

6 (3.8)

3 (4.5)

0.805

 PRISM III score

11.0 (7.0, 15.0)

17.0 (10.0, 21.5)

< 0.001

 Duration of PICU stay (days)

12.0 (7.0, 35.0)

11.5 (4.0, 18.0)

0.062

 Mechanical ventilation, n (%)

82 (51.6)

62 (92.5)

< 0.001

 VIS

12.0 (7.0, 25.0)

22.5 (8.0, 55.0)

0.009

 Lactic acid at admission, (mmol/l)

1.3 (0.9, 2.4)

3.9 (1.6, 8.0)

< 0.001

 Brain natriuretic peptide (pg/mL)

286.0 (62.5, 1015.0)

461.0 (74.0, 1624.5)

0.271

 Proven microorganisms, n (%)

91 (57.2)

45 (67.2)

0.183

Gram-positive

52 (32.7)

26 (38.8)

0.444

 Staphylococci

24 (15.1)

14 (20.9)

0.331

 Streptococci

10 (6.3)

4 (6.0)

0.928

 Enterococcus

15 (9.4)

7 (10.4)

0.814

 Other

3 (1.9)

1 (1.5)

0.837

Gram-negative

34 (21.4)

13 (19.4)

0.858

 Klebsiella

15 (9.4)

2 (3.0)

0.106

 Pseudomonas

5 (3.1)

3 (4.5)

0.697

 E.coli

5 (3.1)

4 (6.0)

0.456

 Acinetobacter

6 (3.8)

4 (6.0)

0.488

 Other

3 (1.9)

0 (0)

0.557

Fungi

5 (3.1)

6 (9.0)

0.088

 Candida

5 (3.1)

6 (9.0)

0.088

 CVP at 6 h, mmHg

8.0 (5.0, 11.0)

10.0 (7.0, 16.0)

< 0.001

Fluid overload, %

 0–24 h

0.7 (−0.6, 2.6)

1.3 (−0.2, 3.6)

0.100

 0–48 h

1.9 (−0.5, 5.7)

3.9 (0.9, 9.3)

0.006

 0–72 h

3.8 (0.3, 7.9)

5.1 (1.8, 10.9)

0.055

  1. The results are presented as the median (interquartile range) or as the number (%). PICU, Pediatric Intensive Care Unit; PRISM III, Pediatric Risk of Mortality III; VIS, Vasoactive Inotropic Scores