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Table 3 Biological data during therapeutic hypothermia and rewarming

From: Transcapillary fluid flux and inflammatory response during neonatal therapeutic hypothermia: an open, longitudinal, observational study

Biological parameters Therapeutic hypothermia, hours after birth Rewarming
7 h 13 h 25 h 49 h 73 h 97 h
pH 7.1 ± 0.2 7.3 ± 0.1 7.3 ± 0.1 7.3 ± 0.1 7.3 ± 0.1 7.3 ± 0.1
pCO2 (kPa) 6.5 ± 2.7 5.8 ± 1.7 5.5 ± 1.0 5.7 ± 1.0 6.0 ± 1.1 6.1 ± 1.2
BE (mmol/l) (−) 12.4 ± 5.1 6.5 ± 3.7 6.7 ± 3.2 5.8 ± 4.1 4.6 ± 2.9 3.5 ± 1.7
Hemoglobin (g/dl) 15.6 ± 2.2 15.4 ± 1.3 15.8 ± 1.8 15.1 ± 1.8 14.4 ± 1.6 13.5 ± 1.7
WBC (× 109/l) 23.7 ± 13.21, 2 24.8 ± 12.73, 4 19.0 ± 7.9 14.9 ± 6.1 11.6 ± 5.5 10.7 ± 3.5
ANC (× 109/l) 12.8 ± 10.4 15.5 ± 7.23, 4 13.8 ± 6.35, 6 10.1 ± 4.8 6.4 ± 2.2 6.9 ± 2.8
Lymph. (× 109/l) 8.7 ± 5.51 4.1 ± 2.7 3.3 ± 1.7 3.4 ± 1.5 2.9 ± 0.7 2.6 ± 0.7
Mono. (× 109/l) 1.5 ± 1.2 2.1 ± 1.23, 4 1.6 ± 0.96 1.0 ± 0.6 0.7 ± 0.4 0.7 ± 0.4
Thrombocytes (× 109/l) 217.0 ± 78.9 178.1 ± 57.8 158.9 ± 63.7 165.2 ± 80.3 143.3 ± 75.6 148.2 ± 75.5
CRP (mg/l) 15.6 ± 13.5 11.0 ± 13.5 10.7 ± 10.7 15.0 ± 12.4 23.6 ± 21.6 23.0 ± 28.7
s-glucose (mmol/l) 11.0 ± 4.8 10.1 ± 6.1 8.1 ± 6.6 5.7 ± 1.0 5.8 ± 2.3 5.3 ± 0.9
s-creatine (mcmol/l) 78.1 ± 16.1 86.9 ± 21.2 81.7 ± 32.1 86.5 ± 46.3 91.3 ± 67.9 85.0 ± 80.7
s-sodium (mmol/l) 135.8 ± 3.2 126.4 ± 32.2 133.9 ± 3.0 134.7 ± 4.0 135.2 ± 5.1 135.9 ± 6.2
s-potassium (mmol/l) 4.3 ± 0.7 4.2 ± 0.7 4.1 ± 0.8 4.0 ± 0.5 4.0 ± 0.6 4.2 ± 0.7
s-albumin (g/l) 28.8 ± 3.67 25.7 ± 3.8
  1. All values represent the mean ± SD. WBC White blood cell count, ANC Absolute neutrophil count, Lymph Lymphocytes, Mono Monocytes, CRP C-reactive protein, 1P < 0.05 at 0–7 h vs. at 73–97 h, 2P < 0.05 at 0–7 h vs. at 49–73 h, 3P < 0.05 at 7–13 h vs. at 74–97 h, 4P < 0.05 at 7–13 h vs. at 49–73 h, 5P < 0.05 at 13–25 h vs. at 74–97 h, 6P < 0.05 at 13–25 h vs. at 49–73 h, 7P = 0.049 at 0–25 h vs. at 49–97 h