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Table 2 General characteristics of the patients

From: Benefits of starting hypothermia treatment within 6 h vs. 6–12 h in newborns with moderate neonatal hypoxic-ischemic encephalopathy

  Control Hypothermia P
< 6 h 6 h < 6 h 6 h
n 48 41 35 28  
Gestational age 38.5 ± 1.4 40 ± 0.8 38.4 ± 1.47 38.1 ± 0.9 0.16
Birth weight (kg) 3.44 ± 0.68 3.13 ± 0.34 3.17 ± 0.42 3.27 ± 0.34 0.15
Gender (male) 30 (62%) 26 (63%) 20 (57%) 23 (82%) 0.19
Cesarean section 18 (37%) 15 (36%) 15 (42%) 8 (28%) 0.71
5-min Apgar grade < 7 34 (50%) 30 (53%) 16 (46%) 13 (46%) 0.35
HIE
 Mild 15 (31%) 17 (41%) 18 (51%) 14 (50%)  
 Moderate 18 (38%) 12 (29%) 11 (31%) 9 (32%) 0.49
 Severe 15 (31%) 12 (29%) 6 (17%) 5 (18%)  
aEEG marking 3.6 ± 3.1 3.8 ± 3.0 4.6 ± 2.5 4.5 ± 3.1 0.45
NSE value 25.6 ± 10.9 38.1 ± 24.6 29.5 ± 27 41 ± 25.6 < 0.01
  1. HIE Hypoxia ischemic encephalopathy, aEEG Amplitude integrated electroencephalography, NSE Neuron-specific enolase
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