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Table 2 General characteristics of the patients

From: Benefits of starting hypothermia treatment within 6 h vs. 6–12 h in newborns with moderate neonatal hypoxic-ischemic encephalopathy

 

Control

Hypothermia

P

< 6 h

6 h

< 6 h

6 h

n

48

41

35

28

 

Gestational age

38.5 ± 1.4

40 ± 0.8

38.4 ± 1.47

38.1 ± 0.9

0.16

Birth weight (kg)

3.44 ± 0.68

3.13 ± 0.34

3.17 ± 0.42

3.27 ± 0.34

0.15

Gender (male)

30 (62%)

26 (63%)

20 (57%)

23 (82%)

0.19

Cesarean section

18 (37%)

15 (36%)

15 (42%)

8 (28%)

0.71

5-min Apgar grade < 7

34 (50%)

30 (53%)

16 (46%)

13 (46%)

0.35

HIE

 Mild

15 (31%)

17 (41%)

18 (51%)

14 (50%)

 

 Moderate

18 (38%)

12 (29%)

11 (31%)

9 (32%)

0.49

 Severe

15 (31%)

12 (29%)

6 (17%)

5 (18%)

 

aEEG marking

3.6 ± 3.1

3.8 ± 3.0

4.6 ± 2.5

4.5 ± 3.1

0.45

NSE value

25.6 ± 10.9

38.1 ± 24.6

29.5 ± 27

41 ± 25.6

< 0.01

  1. HIE Hypoxia ischemic encephalopathy, aEEG Amplitude integrated electroencephalography, NSE Neuron-specific enolase