Table 4 Sensitivity, specificity, positive and negative predictive values of tests at T0, T24 h and T48ha
From: C-reactive protein for late-onset sepsis diagnosis in very low birth weight infants
Test | Sensitivity | Specificity | PPV | NPV |
|---|---|---|---|---|
T0 | ||||
CRP | 49% (41–56) | 76% (72–80) | 43% (37–50) | 79% (75–83) |
CBC | 49% (41–57) | 83% (79–86) | 52% (44–60) | 81% (77–84) |
CBC + CRP | 65% (57–72)† | 66% (61–70)† | 42% (36–48) | 83% (79–87) |
T24 H | ||||
CRP | 84% (78–89) | 70% (66–75) | 52% (46–58) | 92% (89–95) |
CBC | 59% (51–67)† | 79% (75–83) | 53% (46–60) | 84% (80–87) |
CBC + CRP | 87% (80–91) | 60% (55–64)† | 45% (40–51) | 92% (88–95) |
T 48H | ||||
CRP | 73% (66–79) | 79% (74–82) | 57% (50–63) | 88% (85–91) |
CBC | 21% (15–28)† | 92% (88–94)† | 50% (39–62) | 75% (71–79) |
CBC + CRP | 76% (69–82) | 74% (69–78) | 53% (46–59) | 89% (85–92) |