From: Vitamin D in children with growth hormone deficiency due to pituitary stalk interruption syndrome
All PSIS | PSIS included | PSIS excluded | p | ||||
---|---|---|---|---|---|---|---|
(n = 86) | (n = 50) | (n = 36) | |||||
Boys | 54 | 63% | 28 | 56% | 26 | 72% | 0.9 |
Girls | 32 | 37% | 22 | 44% | 10 | 28% | |
Isolated GH deficiency | 39 | 47% | 22 | 44% | 17 | 47% | 0.8 |
Multiple HP deficiency | 47 | 43% | 28 | 56% | 19 | 53% | |
Mean ± SD | Mean ± SD | Mean ± SD | |||||
Age at diagnosis, years | 4.9 ± 4.8 | 5.4 ± 4.9 | 4.2 ± 4.2 | 0.1 | |||
Bone age, years | 3.7 ± 3.9 | 3.3 ± 4.1 | 3.8 ± 3.5 | 0.8 | |||
Height, SDS | −3.1 ± 1.5 | −2.8 ± 1.1 | −3.2 ± 1.8 | 0.7 | |||
BMI, SDS | 0.2 ± 2.8 | 0.2 ± 2.2 | 0.2 ± 3.4 | 0.2 | |||
Growth rate, SDS | − 2.7 ± 1.4 | −2.8 ± 1.4 | −3 ± 1.4 | 0.6 | |||
GH peak, mU/L | 5.9 ± 6.7 | 6.3 ± 6.0 | 4.1 ± 4.6 | 0.3 | |||
IGF1, SDS | − 3.6 ± 1.5 | −3.6 ± 1.6 | −3.6 ± 1.1 | 0.8 | |||
Free thyroxin, pmol/L | 12.3 ± 7.8 | 12.1 ± 7.8 | 12.6 ± 10.8 | 0.5 |