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Table 2 Mean (SD) highest biomarker levels and the mean (SD) time the highest levels were sampled

From: Brain biomarkers and pre-injury cognition are associated with long-term cognitive outcome in children with traumatic brain injury

 

Full Sample (n = 76)

Participants (n = 23)

# of blood draws

3.3 (2.4)

Range: 1–12

3.0 (1.9)

Range: 1–7

 

Highest Level

Time Sampled (Hours)

Highest Level

Time Sampled (Hours)

S100B (pg/ml)

333.9 (512.2)

Range: 19.1–3083.4

25.5 (34.3)

Range: 0.7–177.7

500.7 (770.6)

Range: 22.7–3083.4

19.9 (36.6)

Range: 0.7–177.7

NSE (ng/ml)

48.1 (94.8)

Range: 4.1–722.2

42.6 (52.1)

Range: 0.7–219.8

54.7 (146.3)

Range: 4.1–722.2

48.7 (60.3)

Range: 1.1–219.8

IL-6 (pg/ml)

143.3 (322.0)

Range: 3.7–2471.9

34.5 (45.3)

Range: 1.3–287.8

115.3 (194.5)

Range: 3.7–745.5

45.8 (63.5)

Range: 1.4–287.8

IL-8 (pg/ml)

79.5 (156.4)

Range: 4.4–1056.9

36.6 (44.6)

Range: 1.3–177.7

53.2 (70.5)

Range: 5.8–328.3

35.3 (48.0)

Range: 1.4–177.7

sVCAM-1 (ng/ml)

1088.8 (386.1)

Range: 601.5–2890.9

45.2 (54.3)

Range: 0.7–219.8

1091.3 (456.8)

Range: 601.5–2773.2

50.1 (59.1)

Range: 1.1–219.8

sNCAM (ng/ml)a

280.3 (105.0)

Range: 10.1–583.8

55.9 (50.5)

Range: 1.3–219.8

284.8 (96.4)

Range: 115.3–447.5

52.2 (51.6)

Range: 1.4–219.8

  1. The full names of each biomarker and their abbreviations can be found in the methods section of the manuscript. ng/ml = nanograms per millilitre; pg/ml = picograms per millilitre. No significant differences were found on independent t-tests performed on biomarker levels for those included in this study and those excluded. aMean highest levels of biomarkers were calculated for all except sNCAM, for which the lowest level was used
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BMC Pediatrics

ISSN: 1471-2431

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