Table 1 Demographic and obstetric characteristics of historical cohort, co-morbidities and co-interventions
Demographic and obstetric characteristics | Any stage ROP | Stage 1 ROP at first visit |
|---|---|---|
Newborns, n (%) | 248 | 237 (95.6) |
Gestational age, weeks, mean ± SD | 26.6 ± 2.0 | 26.7 ± 2.0 |
Birth weight, g, mean ± SD | 838 ± 233 | 843 ± 235 |
Male, n (%) | 129 (52.0) | 126 (53.2) |
Caesarean delivery, n (%) | 170 (68.5) | 162 (68.3) |
Stained amniotic fluid, n (%) | 18 (7.3) | 16 (6.7) |
Apgar Score, 1 min, mean ± SD | 4.6 ± 2.3 | 4.6 ± 2.3 |
Apgar Score, 5 min, mean ± SD | 7.4 ± 1.7 | 7.4 ± 1.7 |
Post menstrual age at diagnosis, weeks, mean ± SD | 34.1 ± 2.2 | 34.2 ± 2.3 |
Co-morbidities and co-intervention | ||
Respiratory distress syndrome, n (%) | 239 (96.4) | 228 (96.2) |
Surfactant treatment, n (%) | 208 (83.9) | 198 (83.5) |
Duration of oxygen exposure (days), median (range) | 49.4 (0–291) | 46.7 (0–291) |
Bronchopulmonary dysplasia a, n (%) | 170 (68.5) | 160 (67.5) |
Candida sepsis, n (%) | 12 (4.8) | 12 (5.1) |
Other sepsis, n (%) | 143 (57.7) | 132 (55.7) |
Number of red blood cell transfusions, median (range) | 5 (0–19) | 5 (0–19) |
Intraventricular hemorrhage, grade 3–4, n (%) | 40 (16.1) | 38 (16.0) |
Post-hemorrhagic hydrocephalus, n (%) | 17 (6.8) | 15 (6.3) |
Cholestasis, n (%) | 66 (26.6) | 60 (25.3) |
Necrotizing enterocolitis, n (%) | 32 (12.9) | 31 (13.1) |
Gastrointestinal perforation, n (%) | 26 (10.5) | 25 (10.5) |
Surgical closure of patent ductus arteriosus, n (%) | 56 (22.6) | 52 (21.9) |
Survival, n (%) | 245 (98.8) | 234 (98.7) |