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Table 1 Kaplan-Meier estimates and Cox regression of menarche according to the BMI, WC, TSF and SSFa in the total sample and in girls with recent menarche

From: Timing of menarche in Norwegian girls: associations with body mass index, waist circumference and skinfold thickness

   

Unadjusted modelb

Fully adjusted modelb

Final modelb

N

Median

HR (95% CI)

P

HR (95% CI)

P

HR (95% CI)

P

All girls (N = 1481)

 BMI

  Low

262

14.1

0.40 (0.30–0.55)

<0.001

0.56 (0.39–0.82)

0.001

0.53 (0.38–0.75)

<0.01

  Normal

960

13.1

1.00

 

1.00

 

1.00

 

  High

259

12.6

1.46 (1.16–1.84)

0.001

1.45 (1.03–2.05)

0.01

1.41 (1.07–1.85)

0.01

 WC

  Low

236

13.7

0.54 (0.40–0.71)

<0.001

0.93 (0.67–1.30)

   

  Normal

1000

13.1

1.00

 

1.00

   

  High

244

12.8

1.33 (1.04–1.71)

0.01

0.86 (0.59–1.24)

   

 TSF

  Low

235

13.6

0.59 (0.45–0.78)

<0.001

0.97 (0.72–1.30)

   

  Normal

988

13.1

1.00

 

1.00

   

  High

248

12.7

1.33 (1.04–1.71)

0.01

1.01 (0.73–1.41)

   

 SSF

  Low

237

14

0.40 (0.29–0.54)

<0.001

0.53 (0.37–0.75)

<0.001

0.54 (0.39–0.75)

<0.01

  Normal

965

13.1

1.00

 

1.00

 

1.00

 

  High

273

12.8

1.21 (0.95–1.54)

 

1.03 (0.73–1.45)

 

0.96 (0.72–1.27)

 

Girls with recent menarche (N = 181)

 BMI

  Low

26

13.60

0.76 (0.50–1.17)

 

0.92 (0.51–1.66)

 

0.76 (0.50–1.17)

 

  Normal

118

13.10

1.00

 

1.00

 

1.00

 

  High

37

12.70

1.79 (1.23–2.62)

0.001

1.19 (0.67–2.12)

 

1.79 (1.23–2.62)

0.003

 WC

  Low

19

13.70

0.82 (0.50–1.33)

<0.001

0.99 (0.52–1.87)

   

  Normal

131

13.20

1.00

 

1.00

   

  High

31

12.60

1.96 (1.32–2.94)

0.01

1.40 (0.79–2.48)

   

 TSF

  Low

36

13.50

0.80 (0.55–1.17)

 

1.08 (0.69–1.70)

   

  Normal

119

13.10

1.00

 

1.00

   

  High

23

12.70

1.74 (1.11–2.74)

 

1.11 (0.61–2.04)

   

 SSF

  Low

25

13.50

0.65 (0.42–1.00)

0.050

0.66 (0.39–1.14)

   

  Normal

124

13.10

1.00

 

1.00

   

  High

32

12.70

1.71 (1.15–2.53)

0.01

1.25 (0.73–2.13)

   
  1. aGrouped as low (< −1 SDS), normal (> −1 SDS – > +1 SDS) or high (> +1 SDS) BMI, WC, TSF and SSF. Estimates and models based on the total sample take into account that some girls have not yet reached menarche (censored)
  2. b Unadjusted models are simple Cox regression models for each marker separately; fully adjusted models are multiple Cox regression models including all anthropometric markers; and final models are multiple Cox regression models after backward elimination of statistically not significant covariates (p > 0.1)
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BMC Pediatrics

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