Prevalence and risk factors for non-alcoholic fatty liver in children and youth with obesity

BMC Pediatrics

Table 2 Univariate Associations between NAFLD definition and selected covariates

	N	Meets NAFLD definition: Any (mild/moderate/severe) fatty infiltration or ALT > 25 IU/mL (males)or ALT >22 IU/mL (females)		P Value
		No	Yes
Sex, n (%)				0.57
Male	42	5 (11.9)	37 (88.1)
Female	55	10 (18.2)	45 (81.8)
Age (category), n (%)				1.00
< 10 Years	16	2 (12.5)	14 (87.5)
> =10 Years	81	13 (16.0)	68 (84.0)
Total Cholesterol (mmol/L), mean (SD) normal	97	4.3 (0.6)	4.4 (0.8)	0.63
Triglycerides (mmol/L), mean (SD)	96	1.1 (0.5)	1.5 (0.9)	0.01
HDLC (mmol/L), median (IQR)	97	1.0 (1.0–1.3)	1.0 (0.9–1.2)	0.98
LDLC (mmol/L), mean (SD) normal	96	2.7 (0.6)	2.6 (0.8)	0.72
Non HDL Cholesterol (mmol/L), mean (SD)	84	3.1 (0.6)	3.3 (0.8)	0.37
HOMAIR, n (%)	95			0.40
< 3.16		9 (20)	36 (80)
> = 3.16		6 (12)	44 (88)
AST(IU/mL), median (IQR)	95	23.5 (21.0–26.3)	27.0 (21.0–31.5)	0.18
Adiponectin, median (IQR)	96	16.1 (9.0–21.9)	11.2 (7.3–18.3)	0.23
BMI Z Score, mean (SD)	97	3.7 (1.3)	3.8 (1.4)	0.80

NAFLD Non-Alcoholic Fatty Liver Disease, ALT Alanine Aminotransferase, HDLC High Density Lipoprotein Cholesterol, LDLC Low Density Lipoprotein Cholesterol, HOMA IR Homeostatic Model Assessment Insulin Resistance, AST Aspartate aminotransferase, BMI Body Mass Index.

ISSN: 1471-2431