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Table 4 Changes in Gross Motor Function Measure, Muscle tone before and 6 months after stem cell transplantation according to patients’ characteristics

From: Outcomes of autologous bone marrow mononuclear cells for cerebral palsy: an open label uncontrolled clinical trial

Characteristics Change in GMFM-88 total score
Mean [95% CI]
Change in GMFM-66 percentile
Mean [95% CI]
Change in Ashworth score
Mean [95% CI]
Sex p-value = 0.09 p-value = 0.68 p-value = 0.88
 Male 23.6 [19.3; 27.8] 52.2 [44.5; 60.0] 1.4 [1.2; 1.6]
 Female 32.1 [22.6; 41.6] 56.0 [34.8; 77.2] 1.4 [0.9; 1.9]
Age p-value = 0.07 p-value = 0.32 p-value = 0.89
  < 5 years old 23.6 [19.4; 27.7] 52.5 [44.0; 61.1] 1.4 [1.1; 1.6]
 5–10 years old 27.1 [19.4; 34.8] 52.4 [39.3; 65.5] 1.5 [1.1; 1.8]
  > 10 years old 31.0 [−273.9; 336.0] 60.5 [−390.6; 551.6] 1.5 [−4.9; 7.9]
GMFCS p-value = 0.23 p-value = 0.66 p-value = 0.90
 Level III 33.5 [−49.1; 116.1] 63.5 [−44.5; 171.5] 1.5 [−4.9; 7.9]
 Level IV 34.4 [27.4; 41.4] 57.6 [43.5; 71.7] 1.6 [1.3; 1.9]
 Level V 18.9 [15.6; 22.2] 49.2 [40.5; 57.9] 1.3 [1.1; 1.5]