Table 3 Univariable and Multivariable analysis for associations with mortality

AUC

0·86

0·85

0·25

0·24

2 _6 months

ref

7 _11 months

0·72(0·64–0·82)

<0·001

12_59 months

0·40(0·36–0·45)

2_6 months in high malaria prevalence

ref

ref

7 _11 months in high malaria prevalence

0·46(0·36–0·60)

0·43(0·29–0·63)

12_59 months in high malaria prevalence

0·41(0·33–0·50)

0·37(0·27–0·50)

7 _11 months in Low malaria prevalence

0·34(0·15–0·75)

0·33(0·19–0·57)

12_59 months in Low malaria prevalence

0·29(0·14–0·62)

0·29(0·17–0·49)

Female

ref

ref

ref

Male

0·79(0·72–0·86)

<0·001

0·71(0·64–0·80)

0·67(0·57–0·79)

0 or > = 1 SD

ref

Minus 1 SD

1·35(1·17–1·56)

<0·001

Minus 2 SD

2·26(1·95–2·61)

Minus 3 SD

4·35(3·86–4·92)

0 or > = 1 SD in high malaria prevalence

ref

ref

Minus 1 SD in high malaria prevalence

1·50(1·15–1·95)

1·19(0·85–1·67)

Minus 2 SD in high malaria prevalence

1·25(0·95–1·65)

1·50(1·03–2·17)

Minus 3 SD in high malaria prevalence

2·96(2·27–3·86)

3·01(2·09–4·35)

Minus 1 SD in Low malaria prevalence

0·93(0·45–1·93)

1·06(0·61–1·82)

Minus 2 SD in Low malaria prevalence

1·17 (0·56–2·44)

0·88(0·52–1·51)

Minus 3 SD in Low malaria prevalence

2·36(1·13–4·94)

2·09(1·22–3·56)

0

ref

ref

ref

1

1·44(1·28–1·62)

<0·001

0·99(0·85–1·16)

1·08(0·86–1·37)

2

2·21(1·94–2·50)

1·03(0·86–1·23)

1·27(0·98–1·64)

> = 3

3·67(3·18–4·23)

1·25(1·02–1·55)

1·68(1·25–2·25)

No

ref

ref

ref

Yes

0·96(0·84–1·10)

0·555

0·77(0·66–0·90)

0·76(0·62–0·92)

No

ref

ref

ref

Yes

2·02(1·82–2·25)

<0·001

1·34(1·16–1·56)

1·45(1·20–1·76)

No

ref

ref

ref

Yes

1·13(1·00–1·28)

0·045

1·54(1·32–1·81)

1·35(1·09–1·67)

No

ref

ref

ref

Yes

1·41(1·25–1·58)

<0·001

1·04(0·91–1·20)

1·03(0·86–1·24)

No

ref

ref

ref

Yes

2·84(2·55–3·18)

<0·001

2·61(2·28–2·98)

2·48(2·08–2·96)

None

ref

ref

ref

Some/severe

3·39(3·03–3·79)

<0·001

2·21(1·93–2·53)

2·32(1·92–2·81)

No

ref

ref

ref

Yes

6·36(4·54–8·90)

<0·001

2·64(1·70–4·12)

3·25(1·91–5·53)

Alert

ref

ref

ref

Not alert (VPU)

8·95(7·88–10·17)

<0·001

3·98(3·31–4·77)

3·95(3·16–4·95)

No

ref

Yes

0·23(0·20–0·26)

<0·001

Ability to drink no in high malaria prevalence

ref

ref

Ability to drink yes in high malaria prevalence

0·63(0·49–0·80)

0·65(0·48–0·87)

Ability to drink yes in Low malaria prevalence

0·51(0·24–1·08)

0·44(0·25–0·78)

No/soft

ref

Yes

2·71(2·13–3·44)

<0·001

Stiff neck no in high malaria prevalence

ref

ref

Stiff neck yes in high malaria prevalence

2·17(1·38–3·42)

3·92(2·15–7·16)

Stiff neck yes in low malaria prevalence

3·07(1·28–7·36)

1·53(0·81–2·90)

Immediate

ref

ref

ref

1–2 s

2·25(1·96–2·59)

<0·001

1·29(1·09–1·52)

1·17(0·94–1·44)

> 2 s

6·18(5·28–7·24)

1·80(1·43–2·26)

1·47(1·09–1·98)

<=2 scs

ref

ref

ref

>3 s

3·28(2·80–3·84)

<0·001

1·46(1·15–1·86)

1·68(1·32–2·13)

Indeterminate

0·70(0·51–0·97)

1·17(0·79–1·73)

1·83(1·12–2·99)

No

ref

ref

ref

Yes

2·76(2·44–3·12)

<0·001

1·12(0·96–1·31)

1·24(1·00–1·55)

None

ref

ref

ref

Moderate/severe

2·03(1·55–2·66)

<0·001

1·78(1·30–2·42)

1·64(1·01–2·65)

No

ref

Yes

5·01(4·32–5·81)

<0·001

Severe wasting no in high malaria prevalence

ref

ref

Severe wasting yes in high malaria prevalence

2·35(1·68–3·27)

2·54(1·70–3·82)

Severe wasting yes in low malaria prevalence

1·99(0·97–4·09)

1·66(0·95–2·87)

None

ref

Moderate/severe

3·02(2·39–3·80)

<0·001

Oedema none in high malaria prevalence

ref

ref

Oedema mild/moderate in high malaria prevalence

2·66(1·82–3·89)

3·13(1·95–5·02)

Oedema mild/moderate in Low malaria prevalence

2·45(1·17–5·13)

1·88(1·08–3·25)

High

ref

<0·001

ref

ref

Low

0·90(0·83–0·99)

0·71(0·46–1·08)

0·78(0·43–1·42)

A

ref

ref

ref

B

1·23(1·01–1·61)

<0·001

1·26(0·91–1·73)

1·69(1·04–2·74)

C

1·83(1·53–2·20)

1·74(1·30–2·32)

1·90(1·26–2·85)

D

2·46(2·04–2·96)

1·53(1·16–2·01)

1·99(1·33–2·98)

E

0·53(0·39–0·72)

0·60(0·40–0·90)

0·53(0·28–1·00)

F

1·00(0·79–1·26)

0·91(0·66–1·26)

0·88(0·56–1·39)

G

0·48(0·34–0·67)

0·75(0·49–1·15)

0·81(0·43–1·50)

H

1·41(1·14–1·76)

0·83(0·62–1·11)

0·90(0·52–1·57)

I

1·43(1·20–1·72)

1·23(0·98–1·55)

1·15(0·82–1·60)

J

1·08(0·86–1·37)

0·68(0·50–0·92)

1·05(0·68–1·63)

K

1·52(1·25–1·84)

0·82(0·64–1·07)

0·95(0·68–1·32)

L

1·40(1·15–1·70)

na

na