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Table 1 Methods and timing of sampling. Methods are characterised further in Additional documentation

From: Towards evidence-based vitamin D supplementation in infants: vitamin D intervention in infants (VIDI) — study design and methods of a randomised controlled double-blinded intervention study

 

Birth

6 months of age

12 months of age

24 months of age

Vitamin D

x

 

x

x

Calcium and bone metabolism

x

x

x

x

Inflammatory markers

x

 

x

x

DNA

x

 

x

x

Bone densitometry

  

x

x

Infection records

 

x

x

x

Allergy questionnaire

 

x

x

x

Specific allergic responses (IgA, IgE)

  

x

x

Iron status

  

x

x

Dietary survey

xa

x

x

x

Neurological scales

  

x

x

Family sociodemographic and lifestyle

x

  

x

Neurocognitive development scales

  

x

x

Mental health and behaviour

x

 

x

x

Clinical assessment

 

x

x

x

Health records

x

x

x

x

Viral and bacterial swab

  

x

x

  1. aretrospectively on maternal diet