Fig. 5From: Melatonin alleviates brain and peripheral tissue edema in a neonatal rat model of hypoxic-ischemic brain damage: the involvement of edema related proteinsCerebral glial cells and capillaries assessed via a transmission electron microscope. HIBD could result in a remarkable pathologic change at 24Â h after injury, including clearly decreased organelles and their extraordinary swelling, fused or disappeared intercellular junctions and additional stenosis and contracture of the capillary lumens (e-h) compared with sham group (a-d). Melatonin treatment could reduce the severity of pathology after injury (i-l). Red solid arrows represent tight junctions, red hollow arrows represent capillary lumens, and â–² represents cell vacuolesBack to article page