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Table 1 Summary of baseline characteristics for infants included in analysis

From: Comparison of developmental milestone attainment in early treated HIV-infected infants versus HIV-unexposed infants: a prospective cohort study

 

HIV-infected

HUU

 
 

Na

Median (IQR) or N (%)

Na

Median (IQR) or N (%)

P

Infant characteristics

 Age at enrollment (months)

73

3.7 (3.1, 4.0)

92

1.6 (0.9, 2.1)

<0.0001

 Male

73

35 (48.0)

92

53 (57.6)

0.2

 Birth weight (kg)

68

3.1 (2.7, 3.4)

92

3.2 (3.0, 3.5)

0.02

 Received PMTCT

68

39 (57.4)

-

-

-

 Hemoglobin g/dL

73

9.7 (9, 10.9)

79

11.0 (10.2, 12.7)

<0.0001

 Ever breastfed

64

56 (87.2)

89

89 (100)

0.001b

Infant clinical, immunologic, virologic, and growth status

 Ever hospitalized

73

38 (52.1)

92

0 (0)

<0.001b

 WHO stage 3 or 4

73

30 (41.1)

-

-

-

 Plasma HIV RNA (log10 copies/mL)

69

6.5 (6.0, 7.0)

-

-

-

 CD4%

73

18 (14, 24)

80

42 (35, 47)

<0.0001

 CD4 count (cells/mL)

73

1,311 (801, 1,760)

80

2,515 (2,011, 3,244)

<0.0001

 WAZ

73

−2.0 (−3.3, −0.9)

92

−0.2 (−1.0, 0.3)

<0.0001

 HAZ

73

−1.9 (−3.0, −0.8)

92

−1.4 (−2.4, −0.4)

0.04

 WHZ

73

−0.6 (−1.6, 0.6)

92

1.4 (0.2, 2.3)

<0.0001

 HCZ

73

−0.5 (−1.3, 0.5)

92

0.4 (−0.5, 1.1)

0.0002

Primary caregiver characteristics

 Biological mother

73

71 (97.3)

92

92 (100)

-

 Age (years)

72

26 (22, 30)

89

24 (22, 27)

0.1

 Married

73

57 (78.1)

91

80 (87.9)

0.09

 Education (years)

66

9 (8, 11)

90

9 (8, 12)

0.3

 One-room house

73

56 (76.7)

91

75 (82.4)

0.4

 Household monthly rent (KES)

69

1,500 (1,000, 2,500)

88

2,500 (2,000, 3,500)

<0.0001

 Maternal CD4 count (cells/mm3)

70

370 (246, 478)

-

-

  1. HUU HIV-unexposed uninfected, IQR interquartile range, PMTCT prevention of mother-to-child transmission, WHO World Health Organization, WAZ weight-for-age z-score, HAZ height-for-age z-score, WHZ weight-for-height z-score, HCZ head circumference-for-age z-score, KES Kenyan Shillings
  2. aIncludes infants surviving, or remaining enrolled in the study long enough to define attainment of neck control
  3. bFisher’s exact test