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Table 1 Summary of baseline characteristics for infants included in analysis

From: Comparison of developmental milestone attainment in early treated HIV-infected infants versus HIV-unexposed infants: a prospective cohort study

  HIV-infected HUU  
  Na Median (IQR) or N (%) Na Median (IQR) or N (%) P
Infant characteristics
 Age at enrollment (months) 73 3.7 (3.1, 4.0) 92 1.6 (0.9, 2.1) <0.0001
 Male 73 35 (48.0) 92 53 (57.6) 0.2
 Birth weight (kg) 68 3.1 (2.7, 3.4) 92 3.2 (3.0, 3.5) 0.02
 Received PMTCT 68 39 (57.4) - - -
 Hemoglobin g/dL 73 9.7 (9, 10.9) 79 11.0 (10.2, 12.7) <0.0001
 Ever breastfed 64 56 (87.2) 89 89 (100) 0.001b
Infant clinical, immunologic, virologic, and growth status
 Ever hospitalized 73 38 (52.1) 92 0 (0) <0.001b
 WHO stage 3 or 4 73 30 (41.1) - - -
 Plasma HIV RNA (log10 copies/mL) 69 6.5 (6.0, 7.0) - - -
 CD4% 73 18 (14, 24) 80 42 (35, 47) <0.0001
 CD4 count (cells/mL) 73 1,311 (801, 1,760) 80 2,515 (2,011, 3,244) <0.0001
 WAZ 73 −2.0 (−3.3, −0.9) 92 −0.2 (−1.0, 0.3) <0.0001
 HAZ 73 −1.9 (−3.0, −0.8) 92 −1.4 (−2.4, −0.4) 0.04
 WHZ 73 −0.6 (−1.6, 0.6) 92 1.4 (0.2, 2.3) <0.0001
 HCZ 73 −0.5 (−1.3, 0.5) 92 0.4 (−0.5, 1.1) 0.0002
Primary caregiver characteristics
 Biological mother 73 71 (97.3) 92 92 (100) -
 Age (years) 72 26 (22, 30) 89 24 (22, 27) 0.1
 Married 73 57 (78.1) 91 80 (87.9) 0.09
 Education (years) 66 9 (8, 11) 90 9 (8, 12) 0.3
 One-room house 73 56 (76.7) 91 75 (82.4) 0.4
 Household monthly rent (KES) 69 1,500 (1,000, 2,500) 88 2,500 (2,000, 3,500) <0.0001
 Maternal CD4 count (cells/mm3) 70 370 (246, 478) - -
  1. HUU HIV-unexposed uninfected, IQR interquartile range, PMTCT prevention of mother-to-child transmission, WHO World Health Organization, WAZ weight-for-age z-score, HAZ height-for-age z-score, WHZ weight-for-height z-score, HCZ head circumference-for-age z-score, KES Kenyan Shillings
  2. aIncludes infants surviving, or remaining enrolled in the study long enough to define attainment of neck control
  3. bFisher’s exact test