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Table 3 Family history, maternal, perinatal, newborn and laboratory data of newborns diagnosed with congenital adrenal hyperplasia vs. false positive newborns

From: Neonatal screening for congenital adrenal hyperplasia in Southern Brazil: a population based study with 108,409 infants

Variables

CAH cases

(n = 8)

False positives

(n = 109)

p

Maternal data

 Caesarean delivery (n [%])

4/8 (50.0)

42/70 (60.0)

0.496

Newborn data

 ICU care (n [%])

4/8 (50.0)

71/98 (72.4)

0.281

 Preterm (n [%])

2/8 (25.0)

59/109 (54.1)

0.004

 Birth weight (n [%])

2940 ± 570.34 (n = 8)

2496 ± 761.63 (n = 109)

0.110

 Gestational age (week)

38.0 ± 1.9 (n = 8)

34.8 ± 3.2 (n = 72)

0.007

 Dehydration (n [%])

5/8 (62.5)

3/76 (3.9)

<0.001

 Na (nmol/L)a

122.25 ± 10.15 (n = 8)

136.56 ± 2.28 (n = 54)

0.005

 K (nmol/L)a

6.17 ± 1.21 (n = 8)

5.31 ± 0.67 (n = 54)

0.004

 Serum 17-OHP (ng/mL) (Md [P25-P75])

25.6 (12.8–285) (n = 3)

12.5 (7.4–17.8) (n = 45)

0.006

Family data

 Family history (n [%])

3/8 (37.5)

9/67 (13.4)

0.196

 Consanguinity (n [%])

2/8 (25.0)

0/109 (0%)

<0.001

  1. CAH Congenital adrenal hyperplasia, ICU Intensive care unit. Data are presented as percentage (Fisher’s exact test) or amean ± SD (Student’s t test)