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Table 1 Characteristics of the 114 infants with PDA who were treated with and without PDA ligation

From: Lung function in very low birth weight infants after pharmacological and surgical treatment of patent ductus arteriosus - a retrospective analysis

 

Without PDA ligation

With PDA ligation

p-value

N = 74

N = 40

Neonatal period

 Male

29 (50%)

21 (53%)

0.171

 Gestational age (weeks)

26 (25–28)

25 (24–26)

<0.001

 Birth weight (g)

835 (690–990)

744 (630–860)

0.018

 Birth weight <1000 g

58 (78%)

36 (90%)

0.120

 Prenatal steroidsa

55/72 (76%)

31/38 (82%)

0.531

 Surfactant administrationa

66/72 (92%)

36/39 (92%)

0.906

 Duration of hsPDA (days)

10.5 (7 – 23)

19 (16 – 26)

<0.001

 Mechanical ventilation >24 h

53 (72%)

40 (100%)

<0.001

 Duration of mechanical ventilation (days)

14 (5 – 26)

26.5 (14.5 – 33.5)

<0.001

 Duration of mechanical ventilation up to PDA closure (days)

6 (3 – 10)

12.5 (5.5 – 17.5)

0.003

 CRIB scorea

5 (1–8)

9 (5–11)

0.003

At day of lung function testing

 Age (days)

157 (140 – 176)

160.5 (137 – 186)

0.587

 Postconceptional age (weeks)

48.3 (45.3 – 51.6)

48.0 (45.4 – 51.0)

0.622

 Body weight (g)

4300 (3800 – 5100)

4422 (3795 – 5100)

0.478

 Body length (cm)

54.5 (52.5 – 57.0)

55.3 (52.75 – 58.0)

0.448

  1. Data represent median (interquartile range) or n (%), statistically significant p-values are printed in bold
  2. aTotal number is reduced because some data of outpatients were incomplete