Without PDA ligation | With PDA ligation | p-value | |
---|---|---|---|
N = 74 | N = 40 | ||
Neonatal period | |||
Male | 29 (50%) | 21 (53%) | 0.171 |
Gestational age (weeks) | 26 (25–28) | 25 (24–26) | <0.001 |
Birth weight (g) | 835 (690–990) | 744 (630–860) | 0.018 |
Birth weight <1000 g | 58 (78%) | 36 (90%) | 0.120 |
Prenatal steroidsa | 55/72 (76%) | 31/38 (82%) | 0.531 |
Surfactant administrationa | 66/72 (92%) | 36/39 (92%) | 0.906 |
Duration of hsPDA (days) | 10.5 (7 – 23) | 19 (16 – 26) | <0.001 |
Mechanical ventilation >24 h | 53 (72%) | 40 (100%) | <0.001 |
Duration of mechanical ventilation (days) | 14 (5 – 26) | 26.5 (14.5 – 33.5) | <0.001 |
Duration of mechanical ventilation up to PDA closure (days) | 6 (3 – 10) | 12.5 (5.5 – 17.5) | 0.003 |
CRIB scorea | 5 (1–8) | 9 (5–11) | 0.003 |
At day of lung function testing | |||
Age (days) | 157 (140 – 176) | 160.5 (137 – 186) | 0.587 |
Postconceptional age (weeks) | 48.3 (45.3 – 51.6) | 48.0 (45.4 – 51.0) | 0.622 |
Body weight (g) | 4300 (3800 – 5100) | 4422 (3795 – 5100) | 0.478 |
Body length (cm) | 54.5 (52.5 – 57.0) | 55.3 (52.75 – 58.0) | 0.448 |