TY - JOUR AU - Padari, Helgi AU - Oselin, Kersti AU - Tasa, Tõnis AU - Metsvaht, Tuuli AU - Lõivukene, Krista AU - Lutsar, Irja PY - 2016 DA - 2016/12/08 TI - Coagulase negative staphylococcal sepsis in neonates: do we need to adapt vancomycin dose or target? JO - BMC Pediatrics SP - 206 VL - 16 IS - 1 AB - Despite differences in types of infection and causative organisms, pharmacokinetic-pharmacodynamic (PKPD) targets of vancomycin therapy derived from adult studies are suggested for neonates. We aimed to identify doses needed for the attainment of AUC/MIC > 400 and AUC/MIC > 300 in neonates with sepsis and correlate these targets with recommended doses and treatment outcome. SN - 1471-2431 UR - https://doi.org/10.1186/s12887-016-0753-0 DO - 10.1186/s12887-016-0753-0 ID - Padari2016 ER -