| Fever Cohort (n = 2089) | iNO Trial Cohort (n = 180) |
---|---|---|
Age, yearsa | 1 [0, 2] | 2 [1, 3] |
Male, % (#) | 55Â % (1134) | 57Â % (102) |
Temperature, °C | 37.9 (1.2) | 37.9 (1.2) |
Heart rate, bpm | 159.2 (25.2) | 160.7 (25.0) |
Systolic BP | 105.0 (15.9) | 110.5 (20.2) |
Diastolic BP | 57.4 (13.4) | 58.7 (13.6) |
Respiratory rate | 44 [36, 56] | 48 [38, 62] |
Vomiting | 33Â % (686) | 4Â % (8) |
Diarrhea | 30Â % (614) | 21Â % (38) |
Blantyre coma score | 5 [5, 5] | 2 [2, 3] |
SpO2 | 98 [96, 100] | 99 [98, 100] |
Lactate (mmol/L)b | 2.7 [1.9, 4.9] | 3.6 [2.1, 6.4] |
Lactate >5Â mmol/Lb | 24Â % (485) | 24Â % (43) |
Capillary refill time | ||
 <2 s | 85 % (1724) | 82 % (148) |
 2–3 s | 10 % (194) | 12 % (22) |
 >3 s | 5 % (106) | 6 % (10) |
Lab-confirmed malariac | 67Â % (1240) | 100Â % |
Severe anemiad | 20Â % (428) | 61Â % (109) |
Pretreatment with antibiotic | 33Â % (682) | 43Â % (74) |
Pretreatment with antimalarial | 46.2Â % (956) | 59Â % (105) |