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Table 2 Description of the antibiotic prescriptions in the two periods of the study. n(%)

From: Compliance with the current recommendations for prescribing antibiotics for paediatric community-acquired pneumonia is improving: data from a prospective study in a French network

  Period 1 (10 centres) Period 1 (3 centres) Period 2 (3 centres) p*
Total Compliant Non-compliant Total Compliant Non-compliant Total Compliant Non-compliant
N = 3034 N = 1562 N = 1472 N = 1292 N = 672 N = 620 N = 293 N = 237 N = 56
Mode
 None 126 (4.1) 0 126 (8.6) 9 (0.7) 0 9 (1.5) 1 (0.3) 0 1 (1.8) 0.5
 Oral 2292 (75.5) 1558 (99.7) 734 (49.8) 1035 (80.6) 669 (99.7) 366 (59.0) 257 (87.7) 221 (92.9) 36 (27.3) 0.002
 IV 616 (20.3) 4 (0.3) 612 (41.6) 248 (19.4) 3 (0.3) 245 (39.5) 35 (12) 16 (7.1) 19 (70.9) 0.003
Generic name
 Amoxicillin 1764 (58.1) 1526 (97.7) 238 (17.6) 700 (54.2) 655 (97.5) 45 (7.3) 208 (71) 203 (87.1) 5 (4.1) <0.001
 Amoxicillin + macrolide 98 (3.2) 3 (0.3) 95 (7.1) 49 (3.8) 1 (0.2) 48 (7.7) 13 (4.4) 0 13 (20.4) 0.6
 3rd G cephalosporin 277 (9.1) 1 (0.1) 276 (19.5) 157 (12.2) 0 157 (25.3) 15 (5.1) 6 (2.6) 9 (18.3) <0.001
 Macrolide 93 (3.1) (1.6) 68 (4.9) 46 (3.6) 10 (1.5) 36 (5.8) 16 (5.5) 11 (4.7) 5 (10.2) 0.13
 Pristinamycin 6 (0.2) 5 (0.2) 1 (0.1) 5 (0.4) 4 (0.6) 1 (0.2) 2 (0.7) 0 2 (4.1) 0.5
 C3G + Macrolide 17 (0.6) 0 17 (1.2) 13 (1) 0 13 (2.1) 0 0 0 0.09
 Azithromycin 28 (1) 0 28 (2.1) 0 0 0 5 (1.7) 0 5 (10.2) <0.001
 Amoxicillin-Clavulanate 574 (18.9) 0 574 (40.1) 278 (21.5) 0 278 (44.8) 22 (7.5) 12 (5.2) 10 (16.3) <0.001
 Others 51 (1.7) 4 (0.3) 47 (7.4) 35 (2.71) 2 (0.3) 33 (5.3) 11 (3.8) 0 11 (16.4) 0.4
  1. *p value of the comparison between the total antibiotic prescription in for the 3 centres participating to both periods (chi2)