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Table 1 Demographic data, disease characteristics, and therapeutic interventions for neonates with congenital diaphragmatic hernia (CDH)a

From: Survival prediction of high-risk outborn neonates with congenital diaphragmatic hernia from capillary blood gases

Characteristic

Hospitalization outcome

P value

Survival (n = 25)

Death (n = 19)

Prenatal diagnosis of CDH

9 (36)

9 (47)

0.54

Male sex

16 (64)

11 (58)

0.76

Gestational age, wk

38.6 ± 2.2

37.8 ± 3.4

0.30

Birth weight, kg

3.15 ± 0.67

2.92 ± 0.73

0.29

 Small for gestational age

2 (8)

1 (5)

Apgar score 1 min

6.1 ± 2.6

4.3 ± 2.5

0.02

Apgar score 5 min

6.4 ± 2.5

4.7 ± 1.9

0.02

CDH type

 Left

23 (92)

13 (68)

0.07

 Right

2 (8)

5 (26)

 

 Bilateral

0 (0)

1 (5)

 

Liver-up

8 (32)

16 (84)

<0.001

Probability of survival score, %

64 ± 27

45 ± 19

0.01

 High (67 %-100 %)

13 (52)

3 (16)

 

 Moderate (34 %-66 %)

9 (36)

11 (58)

 

 Low (0 %-33 %)

3 (12)

5 (26)

 

Pulmonary hypertensionb

13 (52)

18 (95)

0.003

Diaphragmatic agenesis

0 (0)

4 (21)

0.03

Peritoneal sac present

4 (16)

0 (0)

0.12

Inhaled nitric oxide

11 (44)

19 (100)

<0.001

Surfactant administration

4 (16)

12 (63)

0.002

Vasoactive support

24 (96)

19 (100)

>0.99

Surgical repairc

 Primary closure

23 (92)

3 (43)

0.01

 Patch repair

2 (8)

3 (43)

 

 Muscle flap repair

0 (0)

1 (14)

 
  1. aContinuous data are presented as mean ± SD; categorical data as number of patients (percentage of sample); bDiagnosed with Doppler echocardiography; cTwelve patients died before surgery; 7 died after surgical repair