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Table 2 Overall frequency of aetiological agents detected among 181 children hospitalized with community-acquired pneumonia

From: Comparison of the frequency of bacterial and viral infections among children with community-acquired pneumonia hospitalized across distinct severity categories: a prospective cross-sectional study

Aetiological agents

Frequency

S. pneumoniae

39 (21.5)

 positive blood culture

8 (4.4)

 positive blood PCR

7 (3.9)

 invasive infectiona

13 (7.2)

 increased paired IgG titres only

26 (14.4)

H. influenzae

13 (7.2)

M. pneumoniae

11 (6.1)

C. trachomatis

9 (5.0)

M. catarrhalis

4 (2.2)

S. negevensis b

3 (1.7)

Rhinovirus

39 (21.5)

RSV

36 (19.9)

 antigen in NPA and increased paired IgG titres

17 (9.4)

 antigen in NPA

11 (6.1)

 increased paired IgG titres

8 (4.4)

Parainfluenza 1, 2, 3

35 (19.3)

 antigen in NPA and increased paired IgG titres

11 (6.0)

 antigen in NPA

2 (1.1)

 increased paired IgG titres

22 (12.2)

Influenza A, B

15 (8.3)

 antigen in NPA and increased paired IgG titres

3 (1.65)

 antigen in NPA

3 (1.65)

 increased paired IgG titres

9 (5.0)

Human bocavirus

17 (9.4)

 low IgG avidity (<15)

17 (9.4)

 positive IgM

16 (8.8)

 qPCR in NPA >10E + 4/ml

15 (8.3)

 positive qPCR in serum

4 (2.2)

 IgG seroconversion

3 (1.65)

 increased paired IgG titres

2 (1.1)

Adenovirus

10 (5.5)

 antigen in NPA and increased paired IgG titres

3 (1.65)

 antigen in NPA

1 (0.55)

 increased paired IgG titres

6 (3.3)

Enterovirus

10 (5.5)

Human metapneumovirus

8 (4.4)

  1. Results in n (%)
  2. RSV respiratory syncytial virus
  3. NPA nasopharyngeal aspirate
  4. qPCR quantitative polymerase chain reaction
  5. aInvasive disease was defined as positive blood culture (bacteraemia) and/or positive blood PCR for pneumococcus
  6. bAll three cases had IgM against S. negevensis detected