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Table 4 Analysis on the risk for invasive fungal infection

From: Efficacy and safety of fluconazole prophylaxis in extremely low birth weight infants: multicenter pre-post cohort study

 

Unadjusted OR (95 % CI)

Adjusted ORa (95 % CI)

P valueb

Fluconazole prophylaxis

1.13 (0.43–2.94)

1.92 (0.30–12.23)

0.49

Gestational age

0.90 (0.86–0.95)

0.87 (0.80–0.95)

0.002

Birth weight

1.0 (0.99–1.0)

1.0 (0.99–1.01)

0.76

Antepartum antibiotic use

7.13 (2.04–24.9)

10.85 (0.94–125.50)

0.06

Umbilical line at postnatal 3rd day

4.44 (1.65–11.95)

0.68 (0.10–4.86)

0.70

H2 blocker use

3.83 (1.25–11.75)

0.76 (0.09–6.09)

0.79

Full feeding reach (≥100 mL/kg/d)

1.05 (1.03–1.08)

1.06 (1.02–1.09)

0.001

Necrotizing enterocolitis (surgical)

8.34 (3.12–22.31)

7.34 (2.00–26.95)

0.003

Invasive bacterial infection

4.89 (1.81–13.18)

1.55 (0.29–8.37)

0.61

Antibiotic duration

1.03 (1.02–1.05)

1.02 (1.00–1.05)

0.09

Vancomycin use

16.55 (2.19–125.23)

3.63 (0.30–43.33)

0.31

  1. a Multivariate logistic regression analysis was done with stepwise method
  2. b for adjusted OR