Skip to main content

Table 2 Growth velocity and body weight change of epileptic children before and after AEDs treatment

From: Potential effects of valproate and oxcarbazepine on growth velocity and bone metabolism in epileptic children- a medical center experience

Patients No. Growth velocity (cm/yr) Body weight change (kg/yr)
  M/F Total Pre-AEDs Post-AEDs ΔHta p-value* Pre-AEDs Post-AEDs ΔWtb p-value*
Pre-puberty 19/9 28 6.7 ± 3.4 5.3 ± 1.3 -1.4 ± 3.3 0.13 1.9 ± 1.8 2.7 ± 2.0 1.2 ± 3.0 0.33
Puberty 13/17 30 6.5 ± 3.4 5.8 ± 2.0 -0.7 ± 2.6 0.30 3.9 ± 2.8 4.7 ± 2.7 0.5 ± 3.0 0.29
Post-puberty 8/7 15 3.7 ± 2.8 3.0 ± 1.9 -0.7 ± 1.8 0.35 4.3 ± 7.4 1.0 ± 2.3 -3.3 ± 6.6 0.27
Overall 40/33 73 6.1 ± 3.4 5.2 ± 2.0 -1.0 ± 2.8 0.04 3.2 ± 3.6 3.4 ± 2.7 0.1 ± 3.9 0.84
  1. Data presented as mean ± SD; aThe difference in growth velocity between pre- and post-AEDs treatment; bThe difference in body weight change between pre- and post-AEDs treatment; *P-value between pre- and post-AEDs treatment