Potential effects of valproate and oxcarbazepine on growth velocity and bone metabolism in epileptic children- a medical center experience

Table 2 Growth velocity and body weight change of epileptic children before and after AEDs treatment

Patients	No.		Growth velocity (cm/yr)				Body weight change (kg/yr)
	M/F	Total	Pre-AEDs	Post-AEDs	ΔHt^a	p-value*	Pre-AEDs	Post-AEDs	ΔWt^b	p-value*
Pre-puberty	19/9	28	6.7 ± 3.4	5.3 ± 1.3	-1.4 ± 3.3	0.13	1.9 ± 1.8	2.7 ± 2.0	1.2 ± 3.0	0.33
Puberty	13/17	30	6.5 ± 3.4	5.8 ± 2.0	-0.7 ± 2.6	0.30	3.9 ± 2.8	4.7 ± 2.7	0.5 ± 3.0	0.29
Post-puberty	8/7	15	3.7 ± 2.8	3.0 ± 1.9	-0.7 ± 1.8	0.35	4.3 ± 7.4	1.0 ± 2.3	-3.3 ± 6.6	0.27
Overall	40/33	73	6.1 ± 3.4	5.2 ± 2.0	-1.0 ± 2.8	0.04	3.2 ± 3.6	3.4 ± 2.7	0.1 ± 3.9	0.84

Data presented as mean ± SD; ^aThe difference in growth velocity between pre- and post-AEDs treatment; ^bThe difference in body weight change between pre- and post-AEDs treatment; *P-value between pre- and post-AEDs treatment

ISSN: 1471-2431