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Table 3 Association between type of delivery, asthma and rhinitis according to parental history of asthma (n = 672)

From: Increased risk of allergic rhinitis among children delivered by cesarean section: a cross-sectional study nested in a birth cohort

Variables

 

No parental history of asthma (n = 496)

 

Parental history of asthma (n = 176)

Effect modification

 

N (%)

OR (95 % CI)

Unadjusted

OR (95 % CI)

Adjusted

N (%)

OR (95 % CI)

Unadjusted

OR (95 % CI)

aAdjusted

p-value**

Active asthma

Cesarean delivery

29 (12.2 %)

1.18 (0.68–2.07)

1.31 (0.71–2.41)

19 (20.4 %)

1.07 (0.72–1.40)

1.14 (0.43–2.99)

0.78

Vaginal delivery

27 (10.5 %)

18 (19,4 %)

Severe asthma

Cesarean delivery

18 (7.6 %)

1.77 (0.85–3.67)

2.14 (0.90–5.06)

11 (12.4 %)

1.33 (0.82–2.18)

2.20 (0.96–5.08)

0.31

Vaginal delivery

11 (4.3 %)

9 (10.3 %)

Chronic rhinitis

Cesarean delivery

99 (41.6 %)

1.84 (1.26–2.64)

1.43 (0.94–2.18)

39 (44.8 %)

1.09 (0.60–1.97)

1.56 (1.04–2.34)

0.10

Vaginal delivery

72 (27.9 %)

38 (42.7 %)

Allergic rhinitis

Cesarean delivery

63 (26.6 %)

1.71 (1.11–2.63)

1.46 (0.91–2.36)

29 (33.3 %)

1.61 (0.63–3.13)

1.60 (1.01–2.55)

0.02

Vaginal delivery

45 (17.4 %)

21 (23.6 %)

  1. ** P-value for effect modification by parental history of asthma in multivariable models
  2. a Adjusted for gestational age, weight at birth, breastfeeding up to the 4th month, mother’s smoking during pregnancy, family income, mother’s schooling level, parity, number of persons who sleep in the room with the child, attendance to nursery to the age of 2 years, pneumonia ever