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Table 5 Multivariate analysis for desaturation, severe desaturation, any TIAEs and severe TIAEs

From: The number of tracheal intubation attempts matters! A prospective multi-institutional pediatric observational study

 

1 attempt (n = 1256)

2 attempts (n = 503)

≥ 3 attempts (n = 321)

Desaturation (SpO2 < 80 %)

1.0 (baseline)

2.9

6.5

(OR, 95 % CI, p-value)

[2.3–3.7, <0.001]

[5.0–8.5, <0.001]

Severe desaturation (SpO2 < 70 %)

1.0 (baseline)

3.1

5.7

(OR, 95 % CI, p-value)

[2.4–4.0, <0.001]

[4.3–7.5, <0.001]

Any TIAEsa

1.0 (baseline)

3.7

5.5

(OR, 95 % CI, p-value)

[2.9–4.9, <0.001]

[4.1–7.4, <0.001]

Severe TIAEs

1.0 (baseline)

1.6

1.8

(OR, 95 % CI, p-value)

[1.1–2.4, 0.02]

[1.1–2.8, 0.01]

  1. Odds ratio, 95 % Confidence interval and p-value were calculated by multivariate logistic regression
  2. Analysis adjusted for history of difficult airway, upper airway obstruction, age as a categorical variable (infant, 1–7 year, 8 or older). Note that history of difficult airway and signs of upper airway obstruction were identified as risk for multiple attempts [23]
  3. Hosmer-Lemeshow goodness of fit test for each model: desaturation (SpO2 < 80 %): Chi2 (29) = 19.90, p = 0.90; severe desaturation (SpO2 < 70 %): Chi2 (29) = 20.69, p = 0.87; Any TIAEs: Chi2 (29) = 24.92, p = 0.68; Severe TIAEs: Chi2 (29) = 20.68, p = 0.87
  4. For outcomes with any TIAEs, we ran a separate multiple logistic regression model without including esophageal intubation with immediate recognition as a part of TIAE definition. The result is shown in Additional file 2: Table S1
  5. OR denotes odds ratio, CI denotes confidence interval
  6. aTIAE denotes adverse Tracheal Intubation Associated Events
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BMC Pediatrics

ISSN: 1471-2431

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