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Table 3 Univariate analysis for desaturation, severe desaturation, adverse tracheal intubation associated events (TIAEs) and severe TIAEs

From: The number of tracheal intubation attempts matters! A prospective multi-institutional pediatric observational study

  1 attempt (n = 1256) 2 attempts (n = 503) ≥ 3 attempts (n = 321) p-value
Desaturations (<80 %)a 202 (16 %) 180 (36 %) 179 (56 %) <0.001
Severe desaturations (<70 %)b 153 (12 %) 150 (30 %) 142 (44 %) <0.001
Any TIAEsc 124 (10 %) 147 (29 %) 122 (38 %) <0.001
Severe TIAEs 67 (5 %) 42 (8 %) 30 (9 %) 0.008
  1. P-value was calculated by Chi-square test
  2. Our sensitivity analysis limited to tracheal intubations (TIs) with pre-oxygenation SpO2 ≥ 90 % yielded a similar result (N = 1753): Desaturation (<80 %) was seen in 15 % of TIs with one attempt, 39 % in TIs with two attempts 59 % in TIs with three attempts (p < 0.001, Chi-square); severe desaturation (<70 %) was seen in 9 % of TIs with one attempt, 29 % in TIs with two attempts 44 % in TIs with three attempts (p < 0.001, Chi-square)
  3. aDesaturation is defined as lowest pulse oximetry <80 % in patients with pulse oximetry >80 % after pre-oxygenation
  4. bSevere desaturation is defined as lowest pulse oximetry <70 % in patients with pulse oximetry >70 % after pre-oxygenation
  5. cTIAE denotes tracheal intubation associated events