Salivary miRNA profiles identify children with autism spectrum disorder, correlate with adaptive behavior, and implicate ASD candidate genes involved in neurodevelopment

Table 1 Subject characteristics

				Vineland adaptive behavior scales
Controls	Age (years)	Sex	ADOS	Comm	Social	ADLs	Comp	Birth age (weeks)	Weight (%ile)	Height (%ile)
Mean	9.2	16M, 5F		110.1	104.4	100.4	105.3	39.2	78.2	68.4
StDev	2.5			10.0	15.7	11.0	12.7	1.3	16.5	20.6
Range	4–13			88–127	81–146	85–124	87–132	36–42	50–100	33–97
ASD
Mean	9.1	19M, 5F	10.6	76.0	77.8	73.6	70.7	38.3	64.7	59.5
StDev	2.4		4.1	15.3	14.3	10.9	10.2	2.5	29.6	25.7
Range	5–13		3–16	49–113	47–108	52–95	48–90	31–41	5–99	10.99
p value	0.182	0.816		0.001	0.001	0.000	0.000	0.294	0.915	0.848

ADLs activities of daily living, ADOS autism diagnostic observation schedule, Comm Vineland Communication score, Social Vineland Socialization score, Comp Vineland Composite score. There were no differences in age or gender composition, birth age, weight or height. Note, the highly significant differences in Vineland scores between control and autism spectrum disorder (ASD) groups

ISSN: 1471-2431