From: Constitutional delay of puberty: presentation and inheritance pattern in 48 familial cases
GIRLS (n = 14) | BOYS (n = 34) | p | |||
---|---|---|---|---|---|
n | m ± SD | n | m ± SD | ||
Age at onset, years | 14 | 13.65 ± 0.77 | 29 | 15.65 ± 1.9 | < 0.01 |
Age at evaluation, years | 14 | 14.05 ± 0.35 | 34 | 15.1 ± 0.42 | < 0.01 |
BMI, SDS | 14 | −1.5 ± 0.7 | 34 | −2 ± 1.41 | NS |
BA delay, years | 12 | 2 ± 1.13 | 27 | 3.05 ± 2.4 | NS |
Tanner pubic hair | 13 | 3 ± 0 | 33 | 2.5 ± 0.7 | NS |
Age at menarche in mothers, years | 13 | 15.75 ± 0.35 | 30 | 14.25 ± 1.8 | 0.01 |
IGF 1, ng/mL | 12 | 190.5 ± 77 | 28 | 233 ± 83 | NS |
LH peak, IU/L | 4 | 5.25 ± 0.63 | 11 | 5.9 ± 1.8 | NS |
FSH peak, IU/L | 4 | 11.6 ± 6.6 | 11 | 1.85 ± 0.07 | NS |
LH/FSH peak ratio | 4 | 0.55 ± 0.35 | 11 | 3.2 ± 1.13 | NS |
Estradiol, pg/mL | 9 | 2.5 ± 0.7 | NA | NA | NA |
Testicular volume index, cm2 | NA | NA | 33 | 7 ± 4.2 | NA |
Testosterone, ng/mL | NA | NA | 28 | 0.46 ± 0.21 | NA |