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Table 1 Characteristics at presentation of 48 probands with familial constitutional delay of puberty

From: Constitutional delay of puberty: presentation and inheritance pattern in 48 familial cases

  GIRLS (n = 14) BOYS (n = 34) p
  n m ± SD n m ± SD  
Age at onset, years 14 13.65 ± 0.77 29 15.65 ± 1.9 < 0.01
Age at evaluation, years 14 14.05 ± 0.35 34 15.1 ± 0.42 < 0.01
BMI, SDS 14 −1.5 ± 0.7 34 −2 ± 1.41 NS
BA delay, years 12 2 ± 1.13 27 3.05 ± 2.4 NS
Tanner pubic hair 13 3 ± 0 33 2.5 ± 0.7 NS
Age at menarche in mothers, years 13 15.75 ± 0.35 30 14.25 ± 1.8 0.01
IGF 1, ng/mL 12 190.5 ± 77 28 233 ± 83 NS
LH peak, IU/L 4 5.25 ± 0.63 11 5.9 ± 1.8 NS
FSH peak, IU/L 4 11.6 ± 6.6 11 1.85 ± 0.07 NS
LH/FSH peak ratio 4 0.55 ± 0.35 11 3.2 ± 1.13 NS
Estradiol, pg/mL 9 2.5 ± 0.7 NA NA NA
Testicular volume index, cm2 NA NA 33 7 ± 4.2 NA
Testosterone, ng/mL NA NA 28 0.46 ± 0.21 NA
  1. NA not applicable, NS not significant