Skip to main content

Table 2 Characteristics of patients with a diagnosis of retinoblastoma (Rb) (n = 140)

From: Retinoblastoma in a pediatric oncology reference center in Southern Brazil

 

N

%

First sign or symptoma

  

 Leukocoria

103

73.6

 Strabismus

29

20.7

 Glaucoma

4

2.9

 Buphthalmos

4

2.9

 Proptosis

4

2.9

 Hyperemia

4

2.9

 Ocular pain

3

2.1

 Anisocoria

3

2.1

 Blindness

2

1.4

 Orbital edema

2

1.4

 Hyphema

2

1.4

 Visual deficiency

1

0.7

 Cervical adenopathy

1

0.7

 Ecchymosis

1

0.7

 Total eyes involved

187

66.8

Ocular laterality

  

 Unilateral Rb

91

65.0

 Right eye

50

54.9

 Left eye

41

45.1

 Bilateral Rb

46

32.9

 Trilateral Rb

3

2.1

Systemic dissemination at diagnosis

  

 Non-metastatic disease

125

89.3

 Metastatic disease

15

10.7

Metastatic sites at diagnosis

  

 Orbit

12

80.0

 CNS

8

53.3

 Bone

4

26.7

 Bone marrow

3

20.0

 Cerebrospinal fluid

2

13.3

 Cervical lymph nodes

1

6.7

  1. Legend: Ages, time to diagnosis and duration of follow-up are expressed in months; Kruskal-Wallis test was used for analysis of ages and time to diagnosis; Log-rank test was used to estimate duration of follow-up; time to diagnosis: time between onset of the first sign or symptom and diagnosis; duration of follow-up: difference between the patient’s age at diagnosis and their age at the time of the last consultation (if alive) or date of death
  2. CNS central nervous system
  3. asome patients had more than one sign or symptom; more than one site per patient