Skip to main content

Table 2 Characteristics of patients with a diagnosis of retinoblastoma (Rb) (n = 140)

From: Retinoblastoma in a pediatric oncology reference center in Southern Brazil

  N %
First sign or symptoma   
 Leukocoria 103 73.6
 Strabismus 29 20.7
 Glaucoma 4 2.9
 Buphthalmos 4 2.9
 Proptosis 4 2.9
 Hyperemia 4 2.9
 Ocular pain 3 2.1
 Anisocoria 3 2.1
 Blindness 2 1.4
 Orbital edema 2 1.4
 Hyphema 2 1.4
 Visual deficiency 1 0.7
 Cervical adenopathy 1 0.7
 Ecchymosis 1 0.7
 Total eyes involved 187 66.8
Ocular laterality   
 Unilateral Rb 91 65.0
 Right eye 50 54.9
 Left eye 41 45.1
 Bilateral Rb 46 32.9
 Trilateral Rb 3 2.1
Systemic dissemination at diagnosis   
 Non-metastatic disease 125 89.3
 Metastatic disease 15 10.7
Metastatic sites at diagnosis   
 Orbit 12 80.0
 CNS 8 53.3
 Bone 4 26.7
 Bone marrow 3 20.0
 Cerebrospinal fluid 2 13.3
 Cervical lymph nodes 1 6.7
  1. Legend: Ages, time to diagnosis and duration of follow-up are expressed in months; Kruskal-Wallis test was used for analysis of ages and time to diagnosis; Log-rank test was used to estimate duration of follow-up; time to diagnosis: time between onset of the first sign or symptom and diagnosis; duration of follow-up: difference between the patient’s age at diagnosis and their age at the time of the last consultation (if alive) or date of death
  2. CNS central nervous system
  3. asome patients had more than one sign or symptom; more than one site per patient