From: Retinoblastoma in a pediatric oncology reference center in Southern Brazil
N | % | |
---|---|---|
First sign or symptoma | ||
Leukocoria | 103 | 73.6 |
Strabismus | 29 | 20.7 |
Glaucoma | 4 | 2.9 |
Buphthalmos | 4 | 2.9 |
Proptosis | 4 | 2.9 |
Hyperemia | 4 | 2.9 |
Ocular pain | 3 | 2.1 |
Anisocoria | 3 | 2.1 |
Blindness | 2 | 1.4 |
Orbital edema | 2 | 1.4 |
Hyphema | 2 | 1.4 |
Visual deficiency | 1 | 0.7 |
Cervical adenopathy | 1 | 0.7 |
Ecchymosis | 1 | 0.7 |
Total eyes involved | 187 | 66.8 |
Ocular laterality | ||
Unilateral Rb | 91 | 65.0 |
Right eye | 50 | 54.9 |
Left eye | 41 | 45.1 |
Bilateral Rb | 46 | 32.9 |
Trilateral Rb | 3 | 2.1 |
Systemic dissemination at diagnosis | ||
Non-metastatic disease | 125 | 89.3 |
Metastatic disease | 15 | 10.7 |
Metastatic sites at diagnosis | ||
Orbit | 12 | 80.0 |
CNS | 8 | 53.3 |
Bone | 4 | 26.7 |
Bone marrow | 3 | 20.0 |
Cerebrospinal fluid | 2 | 13.3 |
Cervical lymph nodes | 1 | 6.7 |