ALL (n = 15,162) | Originator (n = 5362) | Generic (n = 9800) | ||||
---|---|---|---|---|---|---|
Estimate | 95 % CI | Estimate | 95 % CI | Estimate | 95 % CI | |
Years (Analysis performed in comparison to 2004) | ||||||
2005 | −0.06 | [−0.14, 0.02] | 0.00 | [−0.10, 0.09] | −0.13 | [−0.27, 0.00] |
2006 | −0.21c | [−0.29, −0.13] | −0.14b | [−0.24, −0.04] | −0.30c | [−0.44, −0.17] |
2007 | −0.33c | [−0.40, −0.26] | −0.1c | [−0.28, −0.10] | −0.46c | [−0.58, −0.34] |
2008 | −0.45c | [−0.52, −0.38] | −0.27c | [−0.36, −0.19] | −0.56c | [−0.68, −0.44] |
2009 | −0.49c | [−0.56, −0.41] | −0.33c | [−0.43, −0.23] | −0.60c | [−0.73, −0.47] |
2010 | −0.50c | [−0.57, −0.43] | −0.29c | [−0.38, −0.19] | −0.62c | [−0.75, −0.50] |
2011 | −0.45c | [−0.53, −0.38] | −0.45c | [−0.56, −0.35] | −0.50c | [−0.62, −0.38] |
2012 | −0.48c | [−0.56, −0.41] | −0.52c | [−0.63, −0.41] | −0.54c | [−0.66, −0.41] |
Geographical regions (Analysis performed in comparison to sub-Saharan Africa excluding South Africa) | ||||||
East Asia and Pacific | −0.03 | [−0.07, 0.02] | 0.26c | [0.17, 0.35] | −0.11c | [−0.16, −0.06] |
Europe and Central Asia | 0.28c | [0.22, 0.33] | 0.66c | [0.56, 0.76] | 0.08a | [0.02, 0.14] |
Latin America and the Caribbean | 0.07b | [0.02, 0.11] | 0.31c | [0.23, 0.38] | 0.00 | [−0.05, 0.05] |
Middle East and North Africa | 0.08 | [0.00, 0.17] | 0.29c | [0.14, 0.44] | −0.05 | [−0.14, 0.05] |
South Asia | −0.13c | [−0.20, −0.06] | 0.13 | [−0.18, 0.44] | −0.13c | [−0.21, −0.06] |
South Africa | −0.23c | [−0.29, −0.18] | −0.71c | [−0.81, −0.61] | 0.24c | [0.17, 0.31] |
Income group (Analysis done in comparison to low income countries) | ||||||
Lower-middle income countries | 0.04b | [0.02, 0.07] | 0.14c | [0.09, 0.20] | 0.02 | [−0.01, 0.05] |
Upper-middle income countries | 0.17c | [0.12, 0.22] | 0.48c | [0.39, 0.58] | 0.02 | [−0.04, 0.07] |
Formulation type (Analysis done in comparison with single ARVs) | ||||||
Double | 0.01 | [−0.04, 0.05] | 0.10c | [0.05, 0.16] | −0.35c | [−0.42, −0.29] |
Triple | −0.08b | [−0.15, −0.02] | −0.48c | [−0.56, −0.40] | ||
Effects of competition and volume | ||||||
1 additional manufacturer | −0.04c | [−0.04, −0.03] | −0.02c | [−0.03, −0.01] | −0.08c | [−0.09, −0.07] |
Log(quantity purchased) | −0.10c | [−0.10, −0.09] | −0.11c | [−0.12, −0.10] | −0.10c | [−0.10, −0.09] |
Market segment (analysis done in comparison to generic) | ||||||
Originator | 0.72c | [0.70, 0.75] | ||||
Adjusted R2 | 0.35 | 0.20 | 0.16 | |||
Sum of squared residuals | 7413 | 2497 | 4404 |