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Table 1 Multivariate analysis of the factors associated with pricesd of pediatric antiretrovirals

From: An analysis of volumes, prices and pricing trends of the pediatric antiretroviral market in developing countries from 2004 to 2012

  ALL (n = 15,162) Originator (n = 5362) Generic (n = 9800)
Estimate 95 % CI Estimate 95 % CI Estimate 95 % CI
Years (Analysis performed in comparison to 2004)
2005 −0.06 [−0.14, 0.02] 0.00 [−0.10, 0.09] −0.13 [−0.27, 0.00]
2006 −0.21c [−0.29, −0.13] −0.14b [−0.24, −0.04] −0.30c [−0.44, −0.17]
2007 −0.33c [−0.40, −0.26] −0.1c [−0.28, −0.10] −0.46c [−0.58, −0.34]
2008 −0.45c [−0.52, −0.38] −0.27c [−0.36, −0.19] −0.56c [−0.68, −0.44]
2009 −0.49c [−0.56, −0.41] −0.33c [−0.43, −0.23] −0.60c [−0.73, −0.47]
2010 −0.50c [−0.57, −0.43] −0.29c [−0.38, −0.19] −0.62c [−0.75, −0.50]
2011 −0.45c [−0.53, −0.38] −0.45c [−0.56, −0.35] −0.50c [−0.62, −0.38]
2012 −0.48c [−0.56, −0.41] −0.52c [−0.63, −0.41] −0.54c [−0.66, −0.41]
Geographical regions (Analysis performed in comparison to sub-Saharan Africa excluding South Africa)
East Asia and Pacific −0.03 [−0.07, 0.02] 0.26c [0.17, 0.35] −0.11c [−0.16, −0.06]
Europe and Central Asia 0.28c [0.22, 0.33] 0.66c [0.56, 0.76] 0.08a [0.02, 0.14]
Latin America and the Caribbean 0.07b [0.02, 0.11] 0.31c [0.23, 0.38] 0.00 [−0.05, 0.05]
Middle East and North Africa 0.08 [0.00, 0.17] 0.29c [0.14, 0.44] −0.05 [−0.14, 0.05]
South Asia −0.13c [−0.20, −0.06] 0.13 [−0.18, 0.44] −0.13c [−0.21, −0.06]
South Africa −0.23c [−0.29, −0.18] −0.71c [−0.81, −0.61] 0.24c [0.17, 0.31]
Income group (Analysis done in comparison to low income countries)
Lower-middle income countries 0.04b [0.02, 0.07] 0.14c [0.09, 0.20] 0.02 [−0.01, 0.05]
Upper-middle income countries 0.17c [0.12, 0.22] 0.48c [0.39, 0.58] 0.02 [−0.04, 0.07]
Formulation type (Analysis done in comparison with single ARVs)
Double 0.01 [−0.04, 0.05] 0.10c [0.05, 0.16] −0.35c [−0.42, −0.29]
Triple −0.08b [−0.15, −0.02]    −0.48c [−0.56, −0.40]
Effects of competition and volume
1 additional manufacturer −0.04c [−0.04, −0.03] −0.02c [−0.03, −0.01] −0.08c [−0.09, −0.07]
Log(quantity purchased) −0.10c [−0.10, −0.09] −0.11c [−0.12, −0.10] −0.10c [−0.10, −0.09]
Market segment (analysis done in comparison to generic)
Originator 0.72c [0.70, 0.75]  
Adjusted R2 0.35 0.20 0.16
Sum of squared residuals 7413 2497 4404
  1. asignificance level 0.05
  2. bsignificance level 0.01
  3. csignificance level 0.001
  4. dCurrent USD