Table 3 Cohort or Longitudinal Studies Included in the Systematic Review by Selected Study Information
Author | Year | Study design | Agea (years) | Definition | Number | Main effect size Adj OR/HR/GMR/mean | Adj covariates | Key conclusions reported by the study authors | ||
|---|---|---|---|---|---|---|---|---|---|---|
Physical activity | Asthma | Asthma | Total | |||||||
Vogelberg | 2007 | Cohort follow-up 6–7 years | 16–18 | Sports freq(questionnaire) | Physician diagnosed (wz) | 329wz,b | 2,858b | Risk (OR [95 % CI]) of incident wz by sports >3 times per wk vs ≤ once per month (rfgr): 0.8 (0.5–1.3) | Active and passive smoking, BMI, SES, gender | Inverse associations between wz and sport or PC |
Sherriff | 2009 | Cohort follow-up 11.5 years | 11.5 | TV viewing (questionnaire) | Physician diagnosed | 78b | 1,599b | Associations (OR [95 % CI]) of asthma at age 11.5 years with TV viewing at age 3.5 years (>2 hrs/day) vs 1–2 hrs/day (rfgr): 1.8 (1.2–2.6) (P trend = 0.0003) | BMI, maternal asthma/allergies and smoking, social variables | Longer duration of TV viewing associated with development of asthma in later childhood |
Islam | 2009 | Cohort follow-up 10 years | 7–11+ | Team sports (questionnaire) | Physician diagnosed | 142b | 1,580b | Associations (HR [95 % CI]) of GSTP1c genotypes with new-onset asthma by > two team sports vs none (rfgr): 2.66 (1.2–5.9) (P < 0.05) cSubclass of GST | Ethnicity, community of residence, genetic information (GSTM1c and SNP1/SNP3) cSubclass of GST | Children with Val105 variant allele may be protected against increased risk of asthma by exercise |