Table 5 Association between all haematology and biochemistry parameters and explanatory variables age, sex and season
Parameter | Estimated effect on the median (SE)a value of parameter | ||
|---|---|---|---|
Cubic spline of ageb | Genderc | Seasond | |
Total WBC (109/L) | −0.08 (0.006); p < 0.0001 | −0.07 (0.15); p = 0.01 | 0.56 (0.15); p = 0.0002 |
Lymphocytes (109/L) | −0.06 (0.004); p < 0.0001 | −0.05 (0.10); p = 0.65 | 0.31 (0.10); p = 0.004 |
Monocytes (109/L) | −0.004 (0.001); p < 0.0001 | −0.02 (0.02); p = 0.16 | 0.06 (0.02); p = 0.0002 |
Neutrophils (109/L) | −0.004 (0.003); p = 0.13 | −0.22 (0.08); p = 0.004 | 0.26 (0.08); p = 0.0007 |
Eosinophils (109/L) | 0.003 (0.001); p < 0.0001 | 0.02 (0.02); p = 0.31 | −0.02 (0.02); p = 0.24 |
Haemoglobin (g/dL) | 0.041 (0.002); p < 0.0001 | −0.053 (0.068); p = 0.44 | −0.662 (0.069); p < 0.0001 |
Platelets (109/L) | −2.75 (0.29); p < 0.0001 | −8.34 (7.43); p = 0.26 | 44.0 (7.41); p < 0.0001 |
Sodium (mmol/L) | 0.03 (0.01); p < 0.0001 | −0.24 (0.16); p = 0.13 | −0.92 (0.16); p < 0.0001 |
Potassium (mmol/L) | −0.007 (0.001); p < 0.0001 | −0.09 (0.04); p = 0.02 | −0.12 (0.04); p = 0.002 |
Urea (mmol/L) | 0.03 (0.002); p < 0.0001 | 0.12 (0.05); p = 0.02 | −0.19 (0.05); p = 0.003 |
Creatinine (μmol/L) | 0.20 (0.01); p < 0.0001 | 0.77 (0.29); p = 0.01 | −10.9 (0.35); p < 0.0001 |
AST (U/L) | −0.07 (0.02); p = 0.005 | 0.44 (0.65); p = 0.50 | −1.88 (0.65); p = 0.004 |
ALT (U/L) | 0.03 (0.01); p = 0.02 | −0.09 (0.37); p = 0.80 | 5.80 (0.40); p < 0.0001 |
Albumin g/dL | 0.04 (0.01); p < 0.0001 | −0.02 (0.26); p = 0.39 | −1.93 (0.26); p < 0.0001 |