Table 3 Characteristics of children being evaluated for Lyme neuroborreliosis
On admission | Patients (n = 190) |
|---|---|
Age, median years (range) | 10 (1–19) |
Sex | |
female, n (%) | 105 (55) |
male, n (%) | 85 (45) |
Known tick bite, n (%) | 100 (53) |
Major clinical features | |
Acute facial nerve palsy, n (%) | 93 (49) |
Headache, n (%) | 136 (72) |
Fatigue, n (%) | 144 (76) |
Fever, n (%) | 59 (31) |
Neck pain, n (%) | 71 (37) |
Neck stiffness, n (%) | 44 (23) |
Loss of appetite, n (%) | 89 (47) |
Nausea, n (%) | 68 (36) |
Vertigo, n (%) | 63 (33) |
Radiating pain, n (%) | 29 (15) |
Erythema migrans (EM) and/or lymphocytoma, n (%) | 42 (22) |
Laboratory findings | |
Pleocytosis in CSF, n (%) Ω | 82 (43) |
with ≥ 90 % mononuclear cells, n (%) | 75 (91) |
Pleocytosis in CSF, median (range) | 142 (8–890) |
Anti-Borrelia antibodies in CSF, n (%) # | 53 (28) |
IgM, n (%) | 9 (5) |
IgG, n (%) | 12 (6) |
IgM + Ig G, n (%) | 32 (17) |
Anti-Borrelia antibodies in serum, n (%) | 83 (44) |
IgM, n (%) | 22 (12) |
IgG, n (%) | 26 (14) |
IgM + Ig G, n (%) | 35 (18) |
Antibiotic treatment, n (%) | 99 (52) |
Diagnosis § | |
Definite LNB, n (%) | 52 (27) |
Possible LNB, n (%) | 31 (16) |
Non-LNB, n (%) | 107 (56) |