Skip to main content

Table 1 Characteristics of the 40 (21 girls) overweight children and adolescents

From: Multidisciplinary care of obese children and adolescents for one year reduces ectopic fat content in liver and skeletal muscle

  Baseline Follow-up p
Age, years 13.7 (10.0–16.8) 14.6 (10.9–17.8) <0.0001***
BMI SDS 2.80 (1.49–3.85) 2.56 (0.18–4.68) 0.001**
VAT, cm3 83 (21–361) 73 (15–396) 0.01*
SAT, cm3 282 (97–518) 262 (74–527) 0.14
LFC, % 3.0 (0.5–67.0) 3.0 (0.5–32.0) 0.01*
Hepatic steatosis, fraction 28 % (11/40) 20 % (8/40) 0.26
MFC, % 7.4 (1.2–26.3) 4.8 (0.5–39.6) 0.01*
Muscle steatosis, fraction 75 % (30/40) 45 % (18/40) 0.007**
Triglyceride, mmol/l 0.9 (0.2–2.3) 1.0 (0.3–2.0) 0.78
HDL cholesterol, mmol/l 1.2 (0.7–1.7) 1.2 (0.8–2.1) 0.03*
LDL cholesterol, mmol/l 2.3 (1.1–4.2) 2.4 (1.0–3.8) 0.02*
Non-HDL cholesterol, mmol/l 2.8 (1.2–4.7) 2.8 (1.2–4.4) 0.02*
Plasma glucose, mmol/l 5.1 (4.2–6.2) 5.1 (4.4–5.9) 0.42
Serum insulin, pmol/l 83 (11–271) 87 (14–226) 0.99
HbA1c, mmol/l 35 (28–42) 34 (26–40) 0.04*
ALT, U/l 22 (11–126) 22 (10–69) 0.67
GGT, U/l 18 (5–134) 16 (9–33) 0.72
  1. Data are medians (range) due to a non-normal distribution
  2. ALT alanine transaminase; BMI body mass index; GGT gamma-glutamyl transferase; HDL high density lipoprotein; HbA1c glycosylated hemoglobin; IMCL intramyocellular lipid content; LDL low density lipoprotein; LFC liver fat content; MFC muscle fat content; SAT subcutaneous adipose tissue volume; SDS standard deviation score; VAT visceral adipose tissue volume
  3. P value for group differences: *** p <0.001; ** p <0.01; * p <0.05