Table 3 Summary of etiologies of conjugated hyperbilirubinemia in infancy by disease category

Idiopathic Neonatal Hepatitis (INH)

440

26.00 %

Extrahepatic Biliary Atresia (EHBA)

438

25.89 %

Infection

194

11.47 %

TPN associated cholestasis

109

6.44 %

Metabolic disease

74

4.37 %

Alpha-1 Antitrypsin deficiency

70

4.14 %

Perinatal hypoxia/ischemia

62

3.66 %

Interlobular bile duct paucity

42

2.48 %

Choledochal cyst

36

2.13 %

Hypopituitarism/hypothyroidism

33

1.95 %

Hemolysis

24

1.42 %

Inspissated bile syndrome

23

1.36 %

Progressive Familial Intrahepatic Cholestasis (PFIC)

17

1.00 %

Alagille syndrome

16

0.95 %

Cystic Fibrosis

15

0.89 %

Other ^a

99

5.85 %

Total

1692

100.00 %