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Table 4 Stool characteristics at 14, 30, 60, 90, 120, 180, 275, and 365 days of age

From: Growth and tolerance of formula with lactoferrin in infants through one year of age: double-blind, randomized, controlled trial

  Stool frequency   Stool consistency, n (%)  
Age (days) Group (n) Mean ± SEa Overall P hard formed soft unformed or seedy watery Overall P
14 Control (154) 3.1 ± 0.2 0.774 2 (1) 9 (6) 75 (49) 62 (41) 5 (3) 0.092
  LF-0.6 (164) 3.3 ± 0.2   0 (0) 4 (3) 71 (45) 77 (48) 7 (4)  
  LF-1.0 (158) 3.3 ± 0.2   2 (1) 6 (4) 77 (49) 65 (42) 6 (4)  
30 Control (133) 2.4 ± 0.1 0.516 10 (8) 18 (14) 82 (62) 22 (17) 0 (0) <0.001†‡
  LF-0.6 (152) 2.6 ± 0.1   0 (0) 2 (1) 76 (50) 64 (42) 10 (7)  
  LF-1.0 (141) 2.5 ± 0.1   1 (1) 6 (4) 66 (47) 59 (42) 8 (6)  
60 Control (123) 1.9 ± 0.1 0.661 0 (0) 17 (14) 77 (65) 25 (21) 0 (0) <0.001†‡
  LF-0.6 (141) 2.0 ± 0.1   0 (0) 1 (1) 77 (57) 51 (38) 7 (5)  
  LF-1.0 (123) 1.9 ± 0.1   0 (0) 1 (1) 65 (55) 45 (38) 8 (7)  
90 Control (118) 2.1 ± 0.1 0.882 2 (2) 11 (9) 79 (68) 23 (20) 2 (2) <0.001†‡
  LF-0.6 (137) 2.0 ± 0.1   0 (0) 2 (2) 76 (58) 44 (33) 10 (8)  
  LF-1.0 (119) 2.0 ± 0.1   0 (0) 1 (1) 78 (68) 33 (29) 3 (3)  
120 Control (114) 2.0 ± 0.1 0.426 2 (2) 16 (15) 69 (64) 20 (19) 1 (1) <0.001†‡
  LF-0.6 (135) 1.9 ± 0.1   0 (0) 4 (3) 81 (63) 40 (31) 4 (3)  
  LF-1.0 (113) 1.8 ± 0.1   0 (0) 3 (3) 76 (70) 27 (25) 3 (3)  
180 Control (111) 2.0 ± 0.1 0.242 6 (5) 28 (25) 71 (63) 6 (5) 1 (1) <0.001†‡
  LF-0.6 (134) 2.3 ± 0.1   1 (1) 18 (14) 91 (70) 20 (15) 0 (0)  
  LF-1.0 (113) 2.1 ± 0.1   1 (1) 8 (7) 88 (79) 15 (13) 0 (0)  
275 Control (108) 2.2 ± 0.1 0.700 5 (5) 36 (33) 62 (57) 5 (5) 1 (1) 0.267
  LF-0.6 (127) 2.1 ± 0.1   3 (2) 35 (28) 78 (62) 5 (4) 4 (3)  
  LF-1.0 (115) 2.3 ± 0.1   5 (4) 26 (23) 74 (65) 6 (5) 2 (2)  
365 Control (94) 2.1 ± 0.1 0.599 6 (6) 33 (35) 47 (51) 6 (6) 1 (1) 0.352
  LF-0.6 (107) 2.2 ± 0.1   4 (4) 29 (27) 65 (60) 9 (8) 1 (1)  
  LF-1.0 (98) 2.0 ± 0.1   4 (4) 36 (38) 47 (49) 2 (2) 7 (7)  
  1. aMean ± standard error (SE) stool frequency
  2. †Control vs. LF-0.6 significantly different (P < 0.05)
  3. ‡Control vs. LF-1.0 significantly different (P < 0.05)