Table 6 Univariate odds ratios for risk factors for NP carriage of NTHi or Spn in 860 children, adjusted for community
NTHi | Spn | |||||||
|---|---|---|---|---|---|---|---|---|
Risk Factor (n) | OR | 95 % CI | P | OR | 95 % CI | P | ||
Vaccine group (n = 860) | ||||||||
PCV7 | 68 % | 76 % | ||||||
PHiD-CV10 | 73 % | 1.3 | 0.96 to 1.78 | 0.09 | 82 % | 1.4 | 1.00 to 2.06 | 0.05 |
Age group (n = 860) | ||||||||
< 1 year | 71 % | 0.98 | 77 % | 0.48 | ||||
1 to < 2 years | 71 % | 0.98 | 0.67 to 1.43 | 79 % | 1.09 | 0.71 to 1.66 | ||
2 to < 3 years | 70 % | 0.94 | 0.62 to 1.43 | 81 % | 1.30 | 0.81 to 2.09 | ||
Gender (n = 860) | ||||||||
Male | 70 % | 78 % | ||||||
Female | 71 % | 1.00 | 0.74 to 1.34 | 0.98 | 80 % | 1.11 | 0.79 to 1.57 | 0.53 |
Gestational age (n = 760) | ||||||||
> = 32 weeks | 71 % | 81 % | ||||||
< 32 weeks | 65 % | 0.72 | 0.30 to 1.75 | 0.47 | 65 % | 0.40 | 0.16 to 0.98 | 0.05 |
Antibiotics prescribed in previous 5 weeks (n = 860) | ||||||||
None | 69 % | 82 % | ||||||
Any | 74 % | 1.30 | 0.95 to 1.79 | 0.11 | 73 % | 0.58 | 0.41 to 0.82 | 0.002 |
Crowding (number of additional children less than 5 years of age in household) (n = 670) | ||||||||
0 | 67 % | 0.04 | 75 % | 0.25 | ||||
1 | 69 % | 1.12 | 0.76 to 1.66 | 79 % | 1.29 | 0.83 to 2.00 | ||
2 | 61 % | 0.74 | 0.44 to 1.26 | 79 % | 1.19 | 0.64 to 2.22 | ||
3+ | 79 % | 1.70 | 0.97 to 2.36 | 85 % | 1.62 | 0.83 to 2.23 | ||
Child care attendance (n = 673) | ||||||||
< 3 days per week | 69 % | 78 % | ||||||
3 or more days per week | 72 % | 1.18 | 0.70 to 1.99 | 0.53 | 82 % | 1.34 | 0.71 to 2.52 | 0.37 |
Sibling history of OM (“runny ears”) (n = 618) | ||||||||
No | 68 % | 80 % | ||||||
Yes | 70 % | 1.11 | 0.75 to 1.63 | 0.61 | 77 % | 0.91 | 0.59 to 1.41 | 0.68 |
Child near campfire last week (n = 659) | ||||||||
No | 70 % | 77 % | ||||||
Yes | 68 % | 0.90 | 0.63 to 1.28 | 0.56 | 81 % | 1.36 | 0.89 to 2.09 | 0.16 |
Haemoglobin (n = 780) | ||||||||
> =11 mg/dL | 68 % | 79 % | ||||||
<11 mg/dL | 76 % | 1.45 | 1.02 to 2.07 | 0.04 | 80 % | 1.04 | 0.70 to 1.53 | 0.86 |
Maternal smoking (n = 673) | ||||||||
No | 68 % | 79 % | ||||||
Yes | 69 % | 1.05 | 0.75 to 1.48 | 0.76 | 78 % | 0.97 | 0.65 to 1.44 | 0.88 |
Maternal schooling (n = 528) | ||||||||
Year 10 or less | 73 % | 78 % | ||||||
Year 11 or 12 | 63 % | 0.65 | 0.44 to 0.95 | 0.03 | 77 % | 0.94 | 0.61 to 1.47 | 0.80 |
Maternal age at birth of this child (n = 649) | ||||||||
> = 21 yrs | 69 % | 79 % | ||||||
< 21 yrs | 72 % | 1.17 | 0.80 to 1.71 | 0.42 | 80 % | 1.09 | 0.70 to 1.69 | 0.69 |
Breastfed (n = 678) | ||||||||
Never | 60 % | 65 % | ||||||
Some | 69 % | 1.53 | 0.78 to 2.99 | 0.21 | 79 % | 2.34 | 1.14 to 4.80 | 0.02 |
Pacifier (n = 671) | ||||||||
Never | 70 % | 80 % | ||||||
Some | 65 % | 0.81 | 0.53 to 1.25 | 0.34 | 70 % | 0.52 | 0.33 to 0.84 | 0.007 |
PPV23 (n = 163)a | ||||||||
no | 66 % | 76 % | ||||||
yes | 74 % | 1.5 | 0.69 to 3.3 | 0.30 | 77 % | 1.1 | 0.45 to 2.7 | 0.83 |