Table 3 Participant characteristics, general health and antibiotics prescribed, by vaccination group

Age (mo)

421

20 (8)

443

18 (7)

2

0.0001

[1 to 3]

  < 1 year

88

21 %

113

26 %

 1 to < 2 years

182

43 %

218

49 %

 2 to < 3 years

151

36 %

112

25 %

Gestational age (weeks)

346

37.8 (2.8)

418

38.1 (2.2)

0.3

0.03

[0 to 0.7]

  < 32 weeks

15

4 %

8/418

2 %

Birth weight (kg)

358

2.97 (0.64)

423

3.06 (0.61)

0.08

0.03

[0.00 to 0.17]

  < 3 kg

174

49 %

192

45 %

Sex (female)

196/421

47 %

228/443

51 %

5 %

0.15

[−2 to 12]

Runny Nose

160/413

39 %

195/437

45 %

6 %

0.08

[−1 to 12]

Any cough

80/416

19 %

169/439

38 %

19 %

<0.0001

[13 to 25]

Any suppurative OM

209/404

52 %

165/424

39 %

−13 %

0.0002

[-20 to −6]

Any antibiotics prescribed in previous 5 weeks

119/421

28 %

184/443

42 %

13 %

<0.0001

[7 to 20]

 Beta-lactam

95/421

23 %

155/443

35 %

12 %

0.0001

[6 to 18]

 Macrolide

13/421

3 %

18/443

4 %

1 %

0.44

[−1 to 3]

 Topical

17/421

4 %

18/443

4 %

0 %

0.99

[−3 to 3]

Haemoglobin (<11 mg/dL)

115/385

30 %

137/398

34 %

5 %

0.17

[−2 to 11]