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Table 1 The effect of early BCG on anthropometric measurements at 2 months by weight at inclusion

From: Early BCG vaccine to low-birth-weight infants and the effects on growth in the first year of life: a randomised controlled trial

 

Weight at inclusion 2.00–2.49 kg

Weight at inclusion 1.50–1.99 kg

Weight at inclusion <1.50 kg

 

Meana

early BCG

Meana

late BCG

Differenceb(CI: 95 %)

Meana

early BCG

Meana

late BCG

Differenceb(CI: 95 %)

Meana

early BCG

Meana

late BCG

Differenceb(CI: 95 %)

2 months

         

All

         

 Number

643

646

 

242

216

 

56

52

 

 Weight-for-age, z-score

−1.58

−1.64

0.06 (−0.04; 0.16)

−2.97

−2.83

−0.14 (−0.34; 0.06)

−4.63

−4.53

−0.21 (−0.60; 0.18)

 Length-for-age, z-score

−2.06

−2.03

−0.01 (−0.11; 0.09)

−3.45

−3.25

−0.16 (−0.37; 0.05)

−5.39

−5.37

0.02 (−0.42; 0.46)

 Head circumference-for-age, z-score

−0.86

−0.90

0.02 (−0.09; 0.13)

−1.83

−1.92

0.06 (−0.14; 0.26)

−3.36

−3.49

−0.11 (−0.60; 0.38)

 MUACc, cm

11.6

11.5

0.07 (−0.06; 0.19)

10.5

10.6

−0.11 (−0.36; 0.13)

9.2

9.3

−0.20 (−0.71; 0.32)

Boys

         

 Number

284

278

 

106

100

 

21

21

 

 Weight-for-age, z-score

−1.80

−1.73

−0.05 (−0.22; 0.11)

−3.30

−3.03

−0.28 (−0.59; 0.03)

−4.97

−4.86

0.06 (−0.56; 0.68)

 Length-for-age, z-score

−2.37

−2.24

−0.05 (−0.21; 0.11)

−3.81

−3.57

−0.17 (−0.46; 0.11)

−5.89

−5.87

0.51 (−0.12; 1.15)

 Head circumference-for-age, z-score

−2.37

−2.24

−0.09 (−0.27; 0.08)

−2.05

−2.02

−0.02 (−0.34; 0.29)

−3.70

−3.99

0.04 (−0.66; 0.74)

 MUACc, cm

11.7

11.8

−0.08 (−0.28; 0.12)

10.4

10.8

−0.39 (−0.77; −0.01)

9.3

9.3

0.09 (−0.79; 0.97)

Girls

         

 Number

359

368

 

136

116

 

35

31

 

 Weight-for-age, z-score

−1.42

−1.56

0.15 (0.02; 0.28)

−2.71

−2.69

−0.03 (−0.29; 0.23)

−4.42

−4.30

−0.34 (−0.83; 0.15)

 Length-for-age, z-score

−1.81

−1.87

0.04 (−0.09; 0.16)

−3.16

−2.97

−0.16 (−0.45; 0.13)

−5.09

−5.02

−0.32 (−0.90; 0.25)

 Head circumference-for-age, z-score

−0.73

−0.84

0.12 (−0.03; 0.26)

−1.66

−1.84

0.12 (−0.14; 0.38)

−3.16

−3.15

−0.17 (−0.76; 0.43)

 MUACc, cm

11.6

11.4

0.18 (0.02; 0.33)

10.6

10.5

0.10 (−0.21; 0.41)

9.1

9.4

−0.29 (−0.88; 0.30)

  1. aUnadjusted means
  2. bAnalyses are conducted using longitudinal linear regression models containing information on the 2, 6 and 12 months measurements in one model. The analyses are furthermore adjusted for the corresponding measurement at enrolment
  3. cMUAC (Mid upper arm circumference)